Flashcards in Pancreatic Deck (7)
What is 5 year survival of pancreatic cancer?
What are risk factors for pancreatic cancer?
Genetic mutations - BRCA, p16
Familial syndromes - Lynch, hereditary pancreatits, Peutz Jeghers, hereditary telangectasia syndrome
Chronic pancreatitis (alcohol)
High saturated fat, red meat and processed foods
Hepatitis B infection
What is clinical presentation of pancreatic cancer?
asymptomatic until late stage
Most arise in head of pancreas (60-70%)
Jaundice, abdominal pain, steatorrhoea
New onset diabetes
Can invade locally and cause duodenal obstruction
What is the pathology of pancreatic cancer?
Ductal adenocarcinoma (80%)
Neuroendocrine cancers are next most common
How to diagnosis pancreatic cancer?
EUS/ERCP for biopsy
MRI can give more detailed images if considering resection
What is the staging of pancreatic cancer?
T1 - 2cm and confined to pancreas
T3 - involving extra pancreatic structures but not coeliac axis or SMA
T4 - involving coeliac axis or SMA