Table 3 - Anti-Lipid Agents Flashcards Preview

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Flashcards in Table 3 - Anti-Lipid Agents Deck (13)
1

HMG-CoA reductase inhibitors

If it ends in "statin" it does this

Atorvastatin, etc.

2

Bile-acid sequestrants

Cholesytramine, Colesevelam

3

Fibric acids

Fenofibrate, Gemfibrazil

4

Nicotinic acid Vitamin B3

Niacin

5

Cholesterol absorption inhibitor

Exetimibe

6

Other - LOL

Omega 3 fatty acids

7

PCSK9 inhibitor

Evolocumab

8

Inhibits cholesterol synthesis

Statins

9

Binds bile acids inhibiting enterohepatic circulation of cholesterol

Cholestryamine, Colesevelam

10

Not known; theories on changes in various enzymes involved in VLDL and IDL metabolism

Gemfibrozil, fenofibrate

11

Inhibits fatty acid release from adipose tissue and hepatic trig production

Niacin

12

Decreases absorption of cholesterol from GI tract

Exetimibe

13

Human monoclonal antibody that binds to proportion converts subtilisin kexin type 9 (PCSK9) inhibiting the degradation of LDLR - This decreases the number of LDLR's available to clear LDL from blood, thereby lowering LDL-C levels

Evolocumab