Location of the kidneys
In the retroperitoneum.
Due to the liver, the right kidney sits lower than the left, both covering several abdomenal regions
Near what ribs do the kidneys lie?
Anterior to the eleventh and twelth
Where does the renal vein drain?
Into the inferior vena cava
Components of the nephron
Renal corpuscle - tuft of capillaries called glomerulus and glomerular capsule (bowman’s) renal tubule
Basic mechanisms of urine formation
Glomerular filtration
Tubular resorption, secretion
Components of the glomerular wall + capillary
Fenestrations in capillary
Basement membrane
Podocyte foot processes
Glomerular capsule parietal layers cells
Simple squamous
Glomerular capsule visceral layer cells
Fenestrated endothelium of the glomerular capillary
Basement membrane
Podocyte
Proximal convoluted tubule cells
Cuboidal epithelium with increased mitochondria and microvilli, enfolded at the basal plasma membrane.
Distal convoluted tubule cells
Simple cuboidal cells, shorter than those in the PCT with numerous mitochondria and basal enfoldings.
Nephron loop (thin-limb) cells
Simple squamous epithelial, specialised for water reabsorption.
Collecting duct cells
Principal cells (light) (water-sodium balance)
Intercalated cells (dark) with Villi (acid-base balance)
Both cuboidal epithelia.
Structure of cortical nephrons
Corpuscles in the high cortex.
Short loops.
Specialised for reabsorption and secretion.
Structure of juxtamedullary nephrons
Corpuscles near the medulla with long loops into the deep medulla.
Specialised for concentrating urine via the vasa recta.
Vasa recta
Hairpin shaped, straight capillaries in the kidney medulla that run parallel to the loops of henle.
Maintain osmotic gradient and supply blood to the medulla.
Pyelogram
X-ray with contrast for visualisation of renal blockages.
Also known as urogram.
How many pyelogram types, what are they?
Through which spinal region does the pyelogram display?
L2 through L5, mostly lumbar.
Urethra
Segment past the urinary bladder.
Urethra in men vs women?
Much smaller in women which makes UTIs more common but catheterisation easier.
Parts of the male urethra
Prostatic/spongy, penile, membraneous.
What is the narrowest part of the male urethra?
Membraneous
What is microturition?
Voiding of urine
Where does the microturition reflex originate?
The pontine microturition center.