Acute Leukemia Cases--Nikcevich Flashcards

1
Q

11q23 transformation in AML indicates what

A

poor prognosis

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2
Q

11q23 transformation in AML is often caused by…

A

previous chemo

usually alkylating agents

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3
Q

Prognostic feature: Auer rods

A

positive

(better outcome)

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4
Q

t(8;21), t(16;16), t(15;17)

A

good prognostic features

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5
Q

What do monocytes have that makes them easy to see on a smear?

A

nuclear clefts

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6
Q

What type of cell is diagnostic for acute promyelocytic leukemia?

A

Faggot cell

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7
Q

What is donor chimerism?

A

all peripheral blood is from donor tissue

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8
Q

A super duper high WBC with lots of blasts might cause this set of complications

A

hyperviscocity

heart –> ischemia

retina –> blurred vision

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