ID 11 Flashcards
1
Q
What 3 Abx types are concentration dependent killers
A
- AGs
- Quinolones
- Dapto
2
Q
What 4 abxs are AUC:MIC dep
A
- Vanc
- Macrolides
- Tetracyclines
- Polymyxins
3
Q
Only PCN active against Pseudomonas?
A
Zosyn
4
Q
PCN class effects? 2 Cautions and such
A
- Avoid in beta-lactam allergy except pregnant patients with syphilis
- All PCns increase risk of seizure in renal impairment
5
Q
Cephalosporins are not active againts?
A
Enterococcus
6
Q
Oral outpatient cephalosporins? 3
A
- Gen Cephalexin
- Common uses skin infections with MSSA and strep through
- Cefuroxime: Acute otitis media, CAP, sinus infection
- CAP, sinus infection
7
Q
Common uses for cefazolin?
A
Surgical prophylaxis
Parenteral
8
Q
10 in patient pareneteral cephs
A
- 1st gen: Cefazolin
- 2nd gen Cefotetan, Cefoxitin
- 3rd gen: Ceftriaxone and Cefotaxime
- 3rd gen Ceftazidime, 4th gen Cefepime
- Ceftolozan/Tazo, Ceftaz/Avibactam
- Ceftaroline Only beta lactam active against MRSA
9
Q
Class effects of Carbapenems? 4
A
- All cover ESBL producing organisms
- All except ertra cover pseudomonas
- Dont use with PCN allergy
- Seizure risk with higher doses, renal failure or use of imipenem/cilstatin
10
Q
All carbapenems dont cover what 5 organisms?
A
Atypicals, VRE, MRSA, C. DIf, Stenotrophomonas
11
Q
What 3 organisms does ertrapenem not cover?
A
PSeudomonas, Acinetobacter, or Enterococcus
12
Q
3 common uses of Carbapenems
A
- Polymicrobial infections mod severe diabetic foot infections
- Empiric therapy when resistant organsims are suspected
- Resttant pseudomonas or Acinetobacter Not ertra
13
Q
What monobactam can be used with PCN allergy?
A
Aztreonam
14
Q
What are the 3 respiratory quinolones?
A
Moxi, levo gemi
15
Q
8 abxs that do not require renal dose adjustments?
A
- Antistaph PCNS (dicloxacillin, nafcillin)
- Ceftriaxone
- Clindamycin
- Doxy
- Macrolides (azithro, erythro only)
- Metronidazole
- Moxi
- Linezolid
