Flashcards in ALL - Krafts Deck (9)
Define Acute Lymphoblastic Leukemia
Malignant proliferation of lymphoid blasts in the blood and bone marrow
What are the characteristics of ALL?
Classified by immunophenotype: B vs. T-cells
More common in children
Which type of ALL has a worse prognosis?
What markers do you look for in T-lymphoblastic Leukemia?
T-Cell Antigens for CD3,4,5,7,8
What markers do you look for in B-lymphoblastic Leukemia?
B-cell Antigens for CD19,20,21
T-Lymphoblastic Leukemia/Lymphoma Characteristics
Teenage male with mediastinal mass (Thymus)
HIGH WBC count
B-Lymphoblastic Leukemia/Lymphoma Characteristics
MOST common in Children
T-Lymphoblastic is worse = make sure to Immunophenotype!!
Age 1-10 has Good Prognosis
Reasonable WBC count (