Malignant Hematopathology - Krafts Flashcards Preview

IHO Week 3 > Malignant Hematopathology - Krafts > Flashcards

Flashcards in Malignant Hematopathology - Krafts Deck (10)
1

Define Leukemia (cell type, starts where? spreads where? infected cell lines? Types of disease)

Malignancy of hematopoietic cells
Starts in bone marrow, can spread to blood, nodes
Myeloid or lymphoid
Acute or chronic

2

Define Lymphoma (cell type, starts where? spreads where? infected cell line? Types of disease)

Malignancy of hematopoietic cells
Starts in lymph nodes, can spread to blood, marrow
Lymphoid only
Hodgkin or non-Hodgkin

3

How is a malignant diagnosis made?

Clinical setting
Morphology
Immunophenotyping
Molecular Studies
Cytogenetics

4

What type of needle is used in a bone marrow biopsy?

Jamshidi Needle

5

What kinds of cells make up acute leukemias?

Young Cells

6

What kinds of cells make up chronic leukemias?

Mature Cells

7

What kinds of cells make up Hodgkin lymphoma?

Reed-Sternberg Cells

8

What kind of cells make up myeloma?

Plasma Cells

9

What type of stain is used to see monocytes (makes them orange)?

Cytochemical stain with non-specific esterase

10

Philadelphia Chromosome Translocation 9-22 is associated with what disease?

Chronic Myeloid Leukemia