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Flashcards in Basic Pathology Deck (207)
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1

Physiologic vs pathologic hypertrophy: Athlete's heart

Physiologic

2

Physiologic vs pathologic hypertrophy: Pregnant uterus

Physiologic hypertrophy after an initial physiologic hyperplasia

3

2 mechanisms of atrophy resulting in a decrease in size of cells

1) Ubiquitin-proteasome degradation
2) Autophagy

4

Mechanism of atrophy resulting in a decrease in number of cells

Apoptosis

5

Normal left ventricular thickness

1.5 cm

6

Normal right ventricular thickness

0.5 cm

7

Mechanism of metaplasia

Reprogramming of stem cells

8

Epithelial vs mesenchymal: Type of tissue most commonly affected by metaplasia

Epithelial

9

Most common type of metaplasia

Squamous metaplasia

10

Type of metaplasia seen in the cervix

Glandular/columnar metaplasia

11

Mesenchymal metaplasia characterised by heterotropic ossification usually within large muscles

Myositis ossificans

12

Cellular adaptation that takes place in the specialized conjunctival epithelium in vitamin A deficiency

Keratomalacia (metaplasia)

13

Symptom experienced by patients with keratomalacia

Night blindness

14

Vitamin A is essential in the maturation of the immune system hence it (ATRA) is used in the treatment of

Acute promyelocytic leukemia

15

T/F Metaplasia is premalignant

F

16

T/F Dysplasia is premalignant

T

17

Ischemia can cause permanent damage to the brain if not reversed within

3-5 minutes

18

T/F Hyperplasia can progress to dyplasia and CA

T

19

Example of hyperplastic condition that may progress to CA

Endometrial hyperplasia

20

Pathologic hypertrophy vs hyperplasia: BPH

Hyperplasia

21

T/F BPH is premalignant

F

22

Type of hyperplasia in the endometrium that may progress to carcinoma

Complex hyperplasia

23

Most common cause of cellular injury

Hypoxia

24

Final electron acceptor in the ETC

O2

25

Substance that has 100x more affinity to hgb than O2

CO

26

Appearance of skin with CO poisoning

Cherry red

27

First symptom of CO poisoning

Headache

28

Most common cause of hypoxia

Ischemia

29

Most common cause of Budd-Chiari syndrome (renal vein thrombosis)

Polycythemia

30

Spectrum of morphologic changes that follow cell death in living tissue

Necrosis