Ch. 324 - Non-GERD Esophagitis Flashcards Preview

Nelson - The Digestive System > Ch. 324 - Non-GERD Esophagitis > Flashcards

Flashcards in Ch. 324 - Non-GERD Esophagitis Deck (23):
1

Eosinophilic esophagitis is a chronic esophageal disorder characterized by infiltration of the esophageal epithelium by eosinophils, typically in a density exceeding ___

15/HPF

2

Common presentation of EoE in infants

1) Vomiting 2) Feeding problems 3) Poor weight gain

3

Common presentation of EoE in older children and adolescents

1) Solid food dysphagia 2) Occasional food impactions or strictures 3) Chest or epigastric pain

4

EoE: Males vs females

Males

5

EoE: Mean age at diagnosis

7 (range: 1-17)

6

EoE: Duration of symptoms

3 years

7

T/F: Many patients with EoE have other atopic diseases (or a positive FH) and associated food allergies

T

8

T/F Patients with EoE may favorably respond to PPI therapy

T, PPI may have an antieosinophil effect

9

T/F EoE evaluation should include a thorough search for food and environmental allergies via skin prick and patch tests

T

10

Treatment for EoE

Dietary restrictions, successful remission in 70-98% of patients

11

Used successfully for non responders to dietary modification and for nonallergic (primary) EoE, with histologic and symptomatic remission rates reaching 90%

Topical and systemic corticosteroids

12

T/F EoE has a potential for stricture formation

T

13

Organisms that cause infective esophagitis

Candida, Torulopsis glabrata, HSV, CMV, HIV, VZV, diphtheria, Tb

14

Leading cause of infective esophagitis in IMMUNOCOMPETENT AND IMMUNOCOMPROMISED CHILDREN

Candida

15

Causative agent of infective esophagitis that presents with concurrent oropharyngeal infection in the majority of immunocompromised patients

Candida

16

Diagnosis of infectious esophagitis is made by

Endoscopy

17

Agent of infective esophagitis: White plaques

Candida

18

Agent of infective esophagitis: Multiple superficial ulcers

HSV

19

Agent of infective esophagitis: Single deep ulcer

CMV

20

Treatment for infective esophagitis aside from antibiotic

Analgesic and antacid

21

Medications implicated in "pill" esophagitis

1) Tetracycline, 2) KCl, 3) FeSO4, 4) NSAIDs, 5) Alendronate

22

T/F Most often, the offending agent in "pill" esophagitis is a tablet ingested at bedtime with inadequate water

T

23

Treatment of "pill" esophagitis

Supportive, lacking evidence for use of antacids, topical anesthetics, and bland or liquid diets