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Flashcards in GI Neoplasms Deck (101)
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1

Types of GI Neoplasms

Esophageal CA
Carcinoma of the stomach
Pancreatic CA
Liver CA
Small bowel CA
Colorectal CA

2

Type of Benign Esophageal Tumors

Leiomyoma

3

Type of Malignant Esophageal Tumor

Esophageal CA

4

Types of Esophageal Carcinoma

SCC
Adenocarcinoma (more common in US)

5

Risk Factors for SCC

Long-standing esophagitis
Achalasia
Smoking
Alcohol
Diet

6

Define Barrett's Esophagus

Invasion of foreign cells into the lower esophagus

7

Epidemiology of Esophageal CA

Increased prevalence in northern China, India, & Iran
Higher in men
50-80 years old

8

Symptoms of Esophageal CA

Progressive dysphagia
Odynophagia
Regurgitation
Heartburn
Anorexia
Vomiting
Weight loss

9

Diagnostics of Esophageal CA

UGI/barium swallow
Endoscopic US
EGD
CT for staging & mets

10

Treatment of Esophageal CA

Chemo (neoadjuvent, adjuvent)
Radiation (adjuvent)
Surgery

11

Type of Benign Stomach Tumors

Hyperplastic polyp
Leiomyomas
Lipomas

12

Type of Malignant stomach Tumors

CA
Lymphoma
Sarcoma
Carcinoid

13

Carcinoma Tumors

Epithelial cell origin

14

Lymphoma Tumors

Lymphatic system

15

Sarcomas

Connective tissue tumor

16

Carcinoids

Serotonin secreting

17

Gastric Neoplastic Polyps

Tubular
Villous: >2cm & malignant

18

Macroscopic Appearance of Gastric Polyps

In antrum
Pedunculate with malignant potential
Solitary, large, ulcerated

19

Treatment of Gastric Polyps

Endoscopic removal

20

Gastric Leiomyoma arises from what?

Smooth muscle of the GI tract

21

Gastric Leiomyoma Presentation

Possible bleeding

22

Treatment for Gastric Leiomyoma

Local incision with 2-3 cm margin

23

Adenocarcinoma of the Stomach Related to

Low dietary intake veggies & fruit
High dietary intake of starches
More common in males (3:1)
Increased incidence with pernicious anemia & blood type A

24

Histological Typing of Adenocarcinoma of the stomach

Ulcerated carcinoma (25%)
Polipoid carcinoma (25%)
Superficial spreading carcinomas (15%)
Linitis plastica (10%)

25

Ulcerated Carcinoma of the Stomach

Deep penetrating ulcer with shallow edges
Usually through all layers of the stomach

26

Polipoid Carcinoma of the Stomach

Intraluminal tumors
Large in size
Late mets

27

Superficial Spreading Carcinoma of the Stomach

Confined to mucosa & sub-mucosa
Mets 30% at diagnosis
Best prognosis

28

Linitis Plastica Adenocarcinoma of the Stomach

All layers of stomach
Poor prognosis
"Leather-bottle" appearance on Xray

29

Signs/Symptoms of Adenocarcinoma of the Stomach

Vague discomfort
Anorexia: meat aversion
Epigastric mass (late)
Hematemesis (late)
Mets: Virchow's node

30

Spread of Gastric Carcinoma

Through wall of stomach to peritoneum
Pancreas
Local/regional nodes
Liver
Lungs
Across peritoneal cavity (Ovaries)