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Flashcards in Immunology Deck (13)
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1

List some "physical barriers" the eye has to prevent disease

Blink reflex
Chemical properties of eye surface
Small size

2

How do tears physically protect against disease?

Flushing/washout debris
Mucin layer is anti-adhesive - reduces risk of pathogen adherence to eye

3

What chemical components of tears help protect against disease?

Lysozyme
Lactoferrin/transferrin
Complement
Antibacterial lipids
Secretory IgA

4

What is the only part of the eye that has dendritic cells + lymphatic drainage?

Conjunctiva

5

The cornea and sclera are avascular. True/False?

True

6

How does the fact the cornea and sclera are avascular with no MALT help in protecting the eye?

Downregulates immune response

7

What is sympathetic ophthalmia?

Rare bilateral granulomatous uveitis due to trauma/surgery to one eye

8

What are the primary inflammatory mediators in sympathetic ophthalmia?

T cells

9

In sympathetic ophthalmia, the injured eye is known as the excited/sympathetic eye and the fellow eye is known as the excited/sympathetic eye

In sympathetic ophthalmia, the injured eye is known as the excited eye and the fellow eye is known as the sympathetic eye

10

Give an example of type I hypersensitivity affecting the eye

Allergic conjunctivitis

11

Give an example of type II hypersensitivity affecting the eye

Ocular cicatricial pemphigoid

12

Give an example of type III hypersensitivity affecting the eye

Corneal melt

13

Give an example of type IV hypersensitivity affecting the eye

Corneal graft rejection