Flashcards in Immunosuppressant Therapy Deck (9)
What is an immunosuppressant drug?
drug used to prevent production of antibodies
What are two primary reasons that immunosuppressant drugs are used?
1. ORGAN TRANSPLANTS
2. autoimmune diseases
What are the secondary immunodeficiencies?
malnutrition, infection, cancer, renal disease, sarcoidosis, transplant recipients, DM
What is a primary immunodeficiency?
are a group of more than 250 rare, chronic disorders in which part of the body's immune system is missing or functions improperly.
What is a secondary immune deficiency?
disease occurs when the immune system is compromised due to an environmental facto
How do immunodeficiencies present clinically?
- persistant infections that occur more frequently and don't respond to Rx.
-failure to thrive
-physical and developmental disorders noted at birth (face, heart, skeleton)
-doesnt achieve or maintain physical growth and development for age
What is "normal healthy immune system" in a child?
average of 4-8 respiratory infections a year for first 10-12 years
mean duration is 8 days, but can last up to 2 weeks
children in day care or older siblings=more infections
Primary care of immunocompromised child is?
-quick aggressive treatment of infections may require rx
-no live vaccines (no household gets oral polio, other live vaccines fine)
-blood transfusion = leukocyte poor, virus free, irradiated