Intervertebral Disc Flashcards Preview

Spinal Anatomy Exam 3 > Intervertebral Disc > Flashcards

Flashcards in Intervertebral Disc Deck (39):
1

What is the number of true intervertebral discs identified in the adult?

twenty-three

2

In the adult, which vertebral levels will demonstrate a true intervertebral disc?

those between C2 and S1 inclusive

3

What is the intervertebral disc histologically composed of?

cells, collagen fibers, and a hydrated proteoglycan gel

4

What is the cervical nucleus pulposus composed of?

fibrocartilage

5

What is the water concentration in the lumbar nucleus pulposus at birth and after thirty?

birth...88%; thirty...70%

6

What is the consequence of non-aggregated glycosaminoglycans in the lumbar nucleus pulposus?

the nucleus pulposus will lose water under deformation conditions

7

What cell is associated with the nucleus pulposus until about age eleven?

notochord cells

8

What cells are associated with the mature nucleus pulposus?

reticulocyte-fibroblast and chondroblast

9

Which type of collagen is dominant in the nucleus pulposus?

collagen type II

10

What general tissue location is described as having an abundance of collagen type II fibers?

cartilage

11

What is the role of collagen type II fibers based on locations where it is dominant?

it appears to be related to tissues having a deformation-reformation ability

12

What is the appearance of the cervical annulus fibrosus?

a horse-shoe with the anterior margin thick and the lateral margins tapering to the uncinate process; the posterior margin is tin

13

What compensates for the thinness of the posterior part of the cervical annulus fibrosus?

posterior longitudinal ligament

14

What is the organization of the lumbar annulus fibrosus?

it has the 12-14 concentric cylindrical lamellae

15

What is the water concentration in the lumbar annulus fibrosus at birth and after thirty?

birth...78%; thirty...70%

16

What is the organizational pattern for glycosaminoglycans in the lumbar annulus fibrosus?

they typically have a binding site for hyaluronic acid and are thus aggregated

17

Which type of collagen is dominant in the annulus fibrosus?

collagen type I

18

What is the organizational pattern for collagen fibers in the annulus fibrosus?

they are parallel with one another in a single lamellus and angled

19

What is the organization of collagen fibers between lamellae?

collagen fibers will be angled in the opposite direction such that a spiral - counterspiral organization is observed

20

What is the average angle of collagen fibers within the annulus fibrosus?

they average 50 to 60 degrees

21

What is the origin for the cells of the annulus fibrosus?

sclerotomites

22

What part of the vertebral body will the cartilage end plate cover?

the cancellous bone at the top or bottom of the vertebral body

23

What is the principal type of collagen fiber within the cartilage end plate?

the type II collagen fiber

24

What is the direction of collagen fibers within the cartilage end plate?

collagen fibers are aligned anterior to posterior

25

What is the earliest indicator of intervertebral disc pathology or degeneration?

changes in the histology of the cartilage end plate

26

What is the area of maximum metabolic activity in the intervertebral disc?

the transition zone

27

What part of the intervertebral disc is innervated?

the outer lamellae of the annulus fibrosus

28

What part of the cervical intervertebral disc is highly innervated?

the middle third of the annulus fibrosus

29

What are the types of receptor endings in the intervertebral disc?

nociceptors and proprioceptors

30

What is the relationship between size of the intervertebral disc and receptor endings?

The larger the disc, the greater the variety of receptor endings

31

The recurrent meningeal/sinu-vertebral/sinus vertebral nerve has typically been shown to originate from what source?

the gray ramus communicans

32

What part of the intervertebral disc is innervated by the recurrent meningeal/sinu-vertebral/sinus vertebral nerve?

the outer lamella of the annulus fibrosus at the posterior part of the intervertebral disc

33

What forms the anterior neural plexus of the vertebral column?

fibers from the ventral primary ramus

34

What forms the lateral neural plexus of the vertebral column?

fibers from the ventral primary ramus, fibers from the white ramus communicans, fibers from the paradiscal ramus communicans, fibers from the grey ramus communicans

35

What is the name given to the white ramus communicans which becomes embedded within the annulus fibrosus of the intervertebral disc?

the paradiscal ramus communicans

36

What part of the intervertebral disc is innervated by fibers from the paradiscal ramus communicans?

the outer lamellae of the annulus fibrosus at the lateral part of the intervertebral disc

37

What is formed withing the perichordal blastema between the sclerotomites?

the intrasclerotomal fissure of fissure of von Ebner

38

What does the intrasclerotomal fissure of fissure of von Ebner become?

the perichordal disc

39

What will the dense sclerotomite become?

the upper part of the vertebral segment forming below