Multiple Myeloma--Johns and Krafts Flashcards
Rouleaux
multiple myeloma
like Rollos!
What is multiple myeloma?
plasma cell proliferation
Bone finding in multiple myeloma
osteolytic lesions
Diagnostic serum test for multiple myeloma
M-spike
serum protein electrophoresis
Most common Ig in myeloma
IgG
Urine finding MM
proteinuria
Bence-Jones protein
*light chains made in excess*
**may be only sign, some MM only produce excess light chains**
What do you see in BM in MM?
plasma cells and amyloid
How do you stain for amyloid?
congo red
What are Russell bodies?
abnormal Ig buildups in cytoplasms in MM
Waldenström macroglobulinemia path
plasma cell tumor
IgM is produced
(IgM production is rare in other plasma cell tumors)
Classic triad of MM
anemia
bone pain
renal failure
Why might someone with MM have blurred vision?
hyperviscocity syndrome
