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Hematology-Oncology Exam 2 > Ortoski: High-yield Stuff > Flashcards

Flashcards in Ortoski: High-yield Stuff Deck (98)
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1

Geography associated with HIV?

Subsaharan Africa

2

More men or women, which race?

Men more than women, African American predominance

3

Top 3 modes of acquisition of HIV?

1. M to M sexual contact
2. Heterosexual
3. IVDA

4

Around what time was there more treatment, so fewer cases of HIV?

93-94

5

Since HIV causes inflammation, what are 2 areas of issue?

Cardiac and cancer

6

HIV is the BLANK leading cause of death currently

6th- Used to be leading in early 90s in the 25-45 age group

7

Reducing viral load reduces what?

Transmission

8

NRTI

Nucleoside reverse transcriptase inhibitor

9

NNRTI

Non-nucleoside reverse transcriptase inhibitor

10

PI

Protease inhibitor

11

D Drugs

d4t, ddl, ddc, AZT

12

Does AZT have a lot of SE?

YES

13

Nadir CD4

Lowest CD4 count ever

14

Naive

No prior drug exposure

15

Sequestered mutations

Found in minority- not detectable

16

BLD

Below level of detection- less than 20

17

Where is HIV 1 found?

Worldwide

18

Where is HIV 2 found?

Africa- Less easily transmitted

19

Group M

Major group worldwide

20

Group O

Other

21

How many subgroups or clades?

11

22

Group M Subgroup B

Americas, Japan, Austrailia, Carribean, Europe

23

Group M Subgroup C

S. Africa, India

24

Typical transmission modes?

1. Sexual
2. Vertical (mother to child)
3. Transfusion
4. IV drug use

25

If mother's viral load is undetectable, is it less likely to transfer to fetus?

YES

26

Risk factors?

1. 3+ nights in prison
2. Prostitution
3. Other STD

27

What should be emphasize?

Routine voluntary testing

28

What test is the best and confidental?

Serology

29

What is needed for a + result?

2 ELISA screening followed by 1 Western Blot for CONFIRMATION

30

What test is done for infants?

DNA test (newborns have positive antibodies no matter what from mom)