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Flashcards in Test 2 ch 7 Deck (36)
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1

antidepressant classes

SSRI
Serotonin and Norepinephrine RI
Cyclic antidepressants
monoamine oxidase inhibitors

2

fluoxetine (Prozac)

SSRI
used for OCD and major depression
side effects: insomnia, drowsiness, anorexia, nausea
interaction with phenytoin

3

citalopram (Celexa)

SSRI
used for OCD and depression
few drug interactions because of where its metabolized
ideal for patients who are taking other prescriptions

4

paroxetine (Paxil)

SSRI
used for depreassion, OCD, and panic disorder
side effects: nausea, headache, ejaculatory disturbances

5

sertraline (Zoloft)

SSRI
used for depression and OCD
side effect: nausea
take once daily w/o regard of food

6

desvenlafaxine (pristiq)

SNRI
major metabolite of effexor
used for depression and hot flashes
works the same way as effexor but does not produce side effects

7

duloxetine (Cymbalta)

SNRI
used to treat depression and pain from diabetic neuropathy
also weakly inhibits dopamine reuptake
cannot be discontinued abruptly

8

venlafaxine (Effexor)

SNRI
used for depression
termed "prozac with a punch"
may increase blood pressure and manic moments.
at low doses it mostly effects serotonin, and at high doses it also effects norepinephrine

9

doxepin (Sinequan, Zonalon)

tricyclic antidepressant
come in a cream and oral liquid for burning mouth syndrome
oral form should be taken at bedtime because of drowsiness
do not take with carbonated beverages or grape juice which reduce effectiveness

10

mirtazapine (Remeron)

tetracyclic antidepressant
used for mild to severe depression for patients who suffer from nausea

11

Selegiline (Emsam)

MAOI
used primarily in Parkinson's disease
administered orally or as a patch
should not be used with other antidepressants

12

bupropion (Wellbutrin, Zyban, Aplenzin)

dopamine uptake inhibitor
Wellbutrin 3x daily
Wellbutrin SR 2x daily
Wellbutrin XL 1x daily
if more than 300mg in day it must be in 2 doses

13

trazodone (Desyrel)

inhibits serotonin and norepinephrine reuptake
much better side effect profile than TCA's
no anticholinergic effects
may cause orthostatic hypertension
serious interaction with ginkgo

14

lithium

promotes norepinephrine reuptake
used for bipolar and decreases risk of suicide
blood tests must be done 5-10 days then regularly after
salt intake needs to be consistent
absolutely no alcohol

15

divalproex (Depakote)

valproate
used for bipolar disorder
works as an adjuct to lithium
should be taken with food but not carbonated drinks
may cause drowsiness

16

prochlorperazine (Compazine)

in low doses used as antiemetic
in high doses used as antipsychotic

17

thioridazine

only antipsychotic drug that has a ceiling dose which should not exceed 800 mg per day

18

aripiprazole (Abilify)

atypical antipsychotic
dopamine system stabilizer
blocks both dopamine and serotonin receptors
does not prolong QT interval and may cause less weight gain than typical antipsychotics

19

typical antipsychotics

are effective at treating psychosis but have serious long term side effects which limit their use.

20

atypical antipsychotics

Are better tolerated than older agents but are associated with metabolic side effects like weight gain, hyperglycemia, new-onset diabetes, and dyslipidemia.

21

lurasidone (Latuda)

treats schizophrenia
alleviates hallucinations and delusions

22

olanzapine (Zyprexa)

treats schizophrenia
causes fewer movement disorders than similar drugs
side effects: dizziness, drowsiness, constiaption, dry mouth
must avoid alcohol

23

quetiapine (Seroquel)

similar to clozapine but has a lower incidence of hematologic toxicities

24

risperidone (Risperdal)

serotonin/dopamine antagonist
high affinity to serotonin and low to dopamine
treats psychotic disorders and dimensia in the elderly
first drug approved for autism irritability
interacts with Paxil

25

benzodiazepines

antianxiety drugs
treats insomnia, panic disorders, alcohol withdrawal syndrome
must be monitored for depression

26

Buspirone (BuSpar)

antianxiety
selectively antagonizes serotonin receptors w/o affecting receptors for benzodiazepines
take with food
takes two weeks to see the full effect

27

hydroxyzine Pamoate (Vistaril)

used for anxious patients
has sedating qualities and is used as a preoperative sedative

28

propranolol (Inderal)

prophylactic treatment for migraines
beta blocker
treats physical symptoms of anxiety
decreases heart rate

29

Armodafinil (Nuvigil)

approved for excessive sleepiness caused by sleep apnea and narcolepsy
take in the morning
only helps diminish symptoms
if rash appears immediately stop

30

diphenhydramine (Benadryl) and Hydroxyzine (Vistaril)

antihistamine used for sleep
no addiction