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Flashcards in Dermatitis Deck (28)
1

What is meant by hyperkeratosis?

Increased thickness of the keratin layer

2

What is meant by parakeratosis?

Epidermal cell turnover occurs more frequently

3

What is meant by acanthosis?

Increased thickness of epidermis

4

What is meant by papillomatosis?

Irregular epithelial thickening

5

What is meant by spongiosis?

Oedema between keratinocytes

6

Dermatitis is synonymous with eczema. True/False?

True

7

List some features of the acute phase of dermatitis

Red, erythematous lesions
Oedema
Ooze, scaling, crusting

8

List some features of the chronic phase of dermatitis

Thickening (lichenification)
Elevated plaques
Scaling

9

What symptom is always experienced with eczema?

Itch

10

Name the 7 classifications of dermatitis

Contact allergic
Contact irritant
Atopic
Drug-induced
Photosensitive
Lichen simplex
Stasis dermatitis

11

What is the basic pathogenesis behind contact allergic dermatitis?

Type 4 (delayed) hypersensitivity

12

What is the basic pathogenesis behind lichen simplex dermatitis?

Physical trauma to skin, e.g. persistent scratching

13

List some common causes of contact allergic dermatitis

Nickel
Latex
Topical therapies
Plants

14

What causes "weeping" in eczema?

Oedema between keratocytes (spongiosis) spills out onto skin surface

15

What investigation can be used to identify substances causing contact allergic dermatitis?

Patch testing

16

What is involved in patch testing?

Wells containing allergen applied to skin on back and left for 48-96hrs

17

Which dermatitis - contact allergic or irritant - is a non-specific reaction?

Contact irritant dermatitis

18

List examples of things that cause contact irritant dermatitis

Soap
Detergent
Oil
Nappy rash

19

Contact allergic and irritant dermatitis are easy to distinguish. True/False?

False
Often need to patch test

20

List some symptoms and signs of atopic dermatitis

Pruritis
Scaling
Poorly defined erythema
Dry skin
Flexural distribution

21

Atopic dermatitis is associated with other atopic diseases. True/False?

True

22

Secondary infection of atopic eczema is common and occurs due to which organism?

Staph aureus

23

Which virus causes eczema herpeticum?

Herpes simplex virus

24

What does eczema herpeticum look like? (buzzword!)

Monomorphic, punched-out lesions

25

What is the UK diagnostic criteria for atopic eczema?

Itch + at least 3 of:
Flexural rash
History of atopy
Dry skin
Onset before the age of 2

26

List step up therapy for eczema

Emollients + topical steroid;
if infection add antibiotics;
phototherapy;
immunosuppressants if systemic upset

27

What is the most important gene related to atopic eczema?

Filaggrin

28

What is another name for photosensitive dermatitis?

Chronic actinic dermatitis