Flashcards in Intervertebral Disc: Classification and Embryology Deck (18):
1
Based on histology, what is the classification of the intervertebral disc?
cartilaginous (amphiarthrosis) symphysis
2
Based on function, what is a possible classification for the intervertebral disc?
a synovial (diarthrosis) arthrodia
3
How do the parts of the intervertebral disc reflect the parts of a synovial (diarthrosis) joint?
- the annulus fibrosus is comparable to the fibrous capsule
- the nucleus pulposus is comparable to the synovial fluid
- the cartilage end plate is comparable to the articular cartilage
4
What is the earliest indicator of intervertebral disc pathology or degeneration?
changes in the histology of the cartilage end plate
5
What are the divisions of the embryonic somite?
- sclerotome
- myotome
- dermatome
6
What part of the somite will form the vertebral column?
sclerotome
7
What structure is formed following migration of sclerotomes to surround the notochord?
the perichordal blastema
8
What is formed following differential mitosis within the perichordal blastema?
- a loose cranial sclerotomite
- a dense caudal sclerotomite
9
What is formed within the perichordal blastema between the sclerotomites?
the intrasclerotomal fissure or fissure of von Ebner
10
What does the intrasclerotomal fissure become?
the perichordal disc
11
What will the dense sclerotomite become?
the upper part of the vertebral segment forming below
12
What will the loose sclerotomite become?
the lower part of the vertebral segment forming above
13
What structure forms following migration and subsequent mixing of the sclerotomites?
the vertebral blastema
14
What forms the upper part of the vertebral blastema?
the dense caudal sclerotomite of the perichordal blastema above
15
What forms the lower part of the vertebral blastema?
the loose cranial sclerotomite of the perichordal blastema below
16
What part of the intervertebral disc will the notochord form?
the nucleus pulposus
17
What part of the intervertebral disc will the perichordal disc form?
the annulus fibrosus
18