Flashcards in Intervertebral Disc: Nucleus Pulposus Deck (11)
What is the contribution of the nucleus pulposus to intevertebral disc cross-section area?
What is the cervical nucleus pulposus composed of?
What is the water concentration in the lumbar nucleus pulposus at birth and after 30?
- birth: 88%
- after 30: 70%
What is the organizational pattern for glycosaminoglycans in the lumbar nucleus pulposus?
they typically lack a binding site for hyaluronic acid and are thus non-aggregated
What is the consequence of non-aggregated glycosaminoglycans in the lumbar nucleus pulposus?
the nucleus pulposus will lose water under deformation conditions
What cell is associated with the nucleus pulposus until about age 11?
What cells are associated with the mature nucleus pulposus?
reticulocyte-fibroblast and chondroblast
Which type of collagen is dominant in the nucleus pulposus?
collagen type II
What is the organizational pattern for collagen fibers in the nucleus pulposus?
they are irregularly oriented and randomly scattered
What general tissue location is described as having an abundance of collagen type II fibers?