Thanks for using my flashcards, hope you find them useful!
If you spot any errors or have suggestions, please let me know by clicking the speech bubble or sending me a message. It's really helpful.
The questions are written using the official Dundee lectures, so you might find it useful to have them open in the background in case you get stuck.
I write the questions based on what I think the important facts are, but not everything is relevant. Don't waste your time learning tiny details.
On the other hand, this isn't everything you need to know - back it up with stuff from tutorials, other people's questions, Youtube videos, Oxford handbooks etc.
There's a good chance that older decks will be inaccurate (lectures and guidelines change year to year) so I'll try to update them in the future.
Break a leg 👍
Alcohol is a ___.
What is the functional group found in alcohol molecules?
Methanol is ___ and (should / shouldn't) be consumed.
Where may methanol occasionally be found?
Home brew alcohol
What is methanol metabolised into?
Formaldehyde (fixes tissue)
> Formic acid (dissolves you)
What is the main symptom of methanol poisoning?
How is methanol poisoning treated?
Ethanol +/- dialysis
What enzyme metabolises both methanol and ethanol?
By which principle does drinking ethanol help with methanol poisoning?
Competitive inhibition by ethanol
i.e it competes with methanol for the alcohol dehydrogenase enzymes
Which group of women are advised not to drink alcohol?
Why does drinking on a full stomach reduce the rate of alcohol absorption?
Reduced gastric emptying
So more alcohol is metabolised in the stomach instead of being absorbed into the bloodstream
What is the recommended weekly intake of alcohol for men and women?
If a patient is consuming alcohol regularly over a week, they should have several ___ days.
Alcohol is soluble in ___.
Alcohol absorption in the stomach is ___.
Where in the GI tract is mainly responsible for alcohol absorption?
Which drugs increase the rate of gastric emptying and therefore increase the rate at which alcohol is absorbed in the small bowel?
Antihistamines (inc. rate of emptying)
Metoclopramide (for gastroparesis, inc. rate of emptying)
Drinking high concentrations of alcohol will result in it being absorbed (more quickly / more slowly).
Irritates gastric mucosa > delays empyting
What drinks are aerated and tend to be absorbed quickly?
Champagne, prosecco etc.
Do women have a lower tolerance for alcohol than men?
Why do females have a lower tolerance for alcohol than men?
Males have a leaner body mass on average
More water > greater volume for dilution
Females have lower alcohol dehydrogenase activity as well
Which enzyme, which metabolises alcohol, do females have less of compared to men?
Where is most alcohol metabolised?
Apart from the liver, where else is alcohol metabolised?
Apart from in the urine, where else is alcohol excreted?
Alcohol is removed from the blood at 15mg/100ml/hour - how many units is this roughly equivalent to?
1 unit per hour