Flashcards in stats & ethics Deck (62)

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0

## What is the formula for sensitivity?

### True positives / true positives + false negatives

1

## What is the equation for specificity?

### True negatives / true negative + false positive

2

## What is the probability that a test will produce a true negative result when used on a population without disease?

### Specificity

3

## What is the probability that a test will produce a true positive result when used on a population with the disease?

### Sensitivity

4

## What is the probability that someone who had the disease will test positive?

### Positive predictive value

5

## What is the equation for positive predictive value?

### True positive / true positive + false positive

6

## What is the probability that someone who does NOT have a disease will have a negative test result?

### Negative predictive value

7

## What is the equation for negative predictive value?

### True negative / true negative + false negative

8

## What does the P value respresent?

### The chance that the null hypothesis was rejected in error

9

## What P value is significant enough to reject the null hypothesis?

### <0.05

10

## What type of error occurs when the null hypothesis is rejected in error?

### Type 1

11

## What type of error occurs when the null hypothesis was NOT rejected but the null hypothesis is not true?

### Type 2

12

## What number is obtained by adding the sample values and dividing by the size of the sample?

### Mean

13

## What number is the middle value in which half the data is larger and the other have is smaller?

### Median

14

## What is the most frequently occurring number in a sample?

### Mode

15

## What type of study follows persons with risk factors to determine the outcomes?

### Cohort study

16

## What type of study examined those with a disease and then checks for common risk factors?

### Case control study

17

## What is an analysis of data from several studies?

### Meta analysis

18

## Is a 15 y/o who has a child and lives on her own considered an emancipated minor?, why?

### No - must be older than 16

19

## In a comatose infant, what two lab values are most important in diagnosing inborn error of metabolism ?

### Ammonia and anion gap

20

## What inborn errors of metabolism should you consider in a patient with high ammonia and no acidosis?

### Urea cycle defect or transient hyperammonemia

21

## What inborn errors of metabolism would you consider in a patient with high ammonia and metabolic acidosis?

###
Propionic acidemia

Methylmalonic acidemia

Fatty acid oxidation defects

22

## What inborn error of metabolism would you consider in a child with normal serum ammonia and metabolic acidosis?

### Maple syrup urine disease

23

## What inborn errors of metabolism would you consider in a patient with normal ammonia and normal abg?

###
Aminoacidopathy

Galactosemia

Non Ketotic hyperglycinemia

24

## What is the appropriate treatment in a comatose infant with high ammonia ?

###
If >200, reduce ammonia with benzoate and phenylacetate

If >600, dialysis

25

## What is the normal serum ammonia value in a newborn?

### <110

26

## What is the best initial study in a 2 day old infant with acidosis, kerosine and high ammonia?

### Measure urine organic acids

27

## What should be the first study in an infant who presents with the appearance of sepsis but no fever or other signs of infection?

### Serum ammonia level

28

## What is the first step in managing a patient with organic acidemia?

### Hydration

29