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Flashcards in stats & ethics Deck (62)
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0

What is the formula for sensitivity?

True positives / true positives + false negatives

1

What is the equation for specificity?

True negatives / true negative + false positive

2

What is the probability that a test will produce a true negative result when used on a population without disease?

Specificity

3

What is the probability that a test will produce a true positive result when used on a population with the disease?

Sensitivity

4

What is the probability that someone who had the disease will test positive?

Positive predictive value

5

What is the equation for positive predictive value?

True positive / true positive + false positive

6

What is the probability that someone who does NOT have a disease will have a negative test result?

Negative predictive value

7

What is the equation for negative predictive value?

True negative / true negative + false negative

8

What does the P value respresent?

The chance that the null hypothesis was rejected in error

9

What P value is significant enough to reject the null hypothesis?

<0.05

10

What type of error occurs when the null hypothesis is rejected in error?

Type 1

11

What type of error occurs when the null hypothesis was NOT rejected but the null hypothesis is not true?

Type 2

12

What number is obtained by adding the sample values and dividing by the size of the sample?

Mean

13

What number is the middle value in which half the data is larger and the other have is smaller?

Median

14

What is the most frequently occurring number in a sample?

Mode

15

What type of study follows persons with risk factors to determine the outcomes?

Cohort study

16

What type of study examined those with a disease and then checks for common risk factors?

Case control study

17

What is an analysis of data from several studies?

Meta analysis

18

Is a 15 y/o who has a child and lives on her own considered an emancipated minor?, why?

No - must be older than 16

19

In a comatose infant, what two lab values are most important in diagnosing inborn error of metabolism ?

Ammonia and anion gap

20

What inborn errors of metabolism should you consider in a patient with high ammonia and no acidosis?

Urea cycle defect or transient hyperammonemia

21

What inborn errors of metabolism would you consider in a patient with high ammonia and metabolic acidosis?

Propionic acidemia
Methylmalonic acidemia
Fatty acid oxidation defects

22

What inborn error of metabolism would you consider in a child with normal serum ammonia and metabolic acidosis?

Maple syrup urine disease

23

What inborn errors of metabolism would you consider in a patient with normal ammonia and normal abg?

Aminoacidopathy
Galactosemia
Non Ketotic hyperglycinemia

24

What is the appropriate treatment in a comatose infant with high ammonia ?

If >200, reduce ammonia with benzoate and phenylacetate
If >600, dialysis

25

What is the normal serum ammonia value in a newborn?

<110

26

What is the best initial study in a 2 day old infant with acidosis, kerosine and high ammonia?

Measure urine organic acids

27

What should be the first study in an infant who presents with the appearance of sepsis but no fever or other signs of infection?

Serum ammonia level

28

What is the first step in managing a patient with organic acidemia?

Hydration

29

When would organic acidemias present?

First 2 days of life after introduction of protein in the diet