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HMS Oncology > Tumor Progression > Flashcards

Flashcards in Tumor Progression Deck (12)
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1
Q

Stage IV

A

Distal metastasis

2
Q

Mohs surgery

A

Procedure in which a tumor is removed and examined intraoperatively by a pathologist to ensure surgical margins are free of cancer-containing tissue, with additional tissue excised as necessary to obtain this outcome.

3
Q

Clinical staging vs pathologic staging

A

Clinical: Estimate based on results of physical exams, maging, and biopsies

Pathologic: Obtained via surgical analysis and intraoperative biopsy. More precise.

4
Q

If there is a melanoma in situ, it is automatically. . .

A

TIS, therefore Stage 0.

5
Q

Stage II

A

Local metastasis

6
Q

Stage 0

A

In situ disease. It is not yet cancer, but is a precursor lesion that if untreated is likely to progress

7
Q

Stage III

A

Regional metastasis

8
Q

Ipilimumab

A

Anti-CTLA-4

(checkpoint blockade)

9
Q

If invasinve cancer is identified in one area, the next step is to. . .

A

survey the sentinel lymph node for that area.

10
Q

TNM system for melanoma

A

T: Extent of tumor (thickness, ulceration)

N: Spread to regional lymph nodes

M: Metastasis

11
Q

Stage I

A

Local disease (progression through basement membrane)

12
Q

Breslow measurement

A