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HMS Oncology > Tumor Progression > Flashcards

Flashcards in Tumor Progression Deck (12):
1

Stage IV

Distal metastasis

2

Mohs surgery

Procedure in which a tumor is removed and examined intraoperatively by a pathologist to ensure surgical margins are free of cancer-containing tissue, with additional tissue excised as necessary to obtain this outcome.

3

Clinical staging vs pathologic staging

Clinical:  Estimate based on results of physical exams, maging, and biopsies

Pathologic:  Obtained via surgical analysis and intraoperative biopsy.  More precise.

4

If there is a melanoma in situ, it is automatically. . .

TIS, therefore Stage 0.

5

Stage II

Local metastasis

6

Stage 0

In situ disease. It is not yet cancer, but is a precursor lesion that if untreated is likely to progress

7

Stage III

Regional metastasis 

8

Ipilimumab

Anti-CTLA-4

(checkpoint blockade)

9

If invasinve cancer is identified in one area, the next step is to. . .

survey the sentinel lymph node for that area.

10

TNM system for melanoma

T:  Extent of tumor (thickness, ulceration)

N:  Spread to regional lymph nodes

M:  Metastasis

11

Stage I

Local disease (progression through basement membrane)

12

Breslow measurement