Flashcards in Alcohol Dependence Deck (7)
What drugs are used for alcohol withdrawal?
-Diazepam / Chlorodiazepam
-Oxazepam (if liver damage present)
What supportive treatment is provided for alcohol abuse patients? Why?
-IM/IV Pabrinex (C, B1, B2, B3, B6)
-B vitamin body stores are scarce
Why is it essential to provide Thiamine to alcohol abuse patients?
Their B vitamines are likely to be depleted.
Thiamine is a coenzyme involved in the Krebs cycle.
Metabolism in the absence of Thiamine is anaerobic, producing lactic acid. Brain damage can follow.
What is Wernicke-Korsakoff syndrome? What's the treatment?
Thiamine deficiency syndrome
What pharmacological treatment is used in relapse prevention?
Disulfiram - aggravates immediate hangover
Acamprosate - neuroprotective
What is delirium tremens?
Rapid onset of confusion following withdrawal of alcohol