Flashcards in Amenorrhea, Oligomenorrhea Deck (56)
What is primary amenorrhea
no menses by age 13 in absence of secondary sexual characteristics or NO menses by age 15 with secondary sexual characteristics
What is secondary amenorrhea
no menses for >60mo or 3 cycles after documented menarche
what is oligomenorrhea?
episodic vaginal bleeding occurring at intervals >35d
How do you remember puberty stages
boobs, pubes, flow grow
Tanner stage 3?
Breast; no contour, enlargement of breast and areola
When does sexual differentiation occur in embryology?
What happens when males differential?
Wolffian (mesonephric) ducts; develops into epididymis, vas deferens, seminal vesicle, ejaculatory duct
What do wolffian (mesonephric) ducts differential into?
epididymis, vas deferens, seminal vesicles, ejaculatory duct.
What cells lead to male sexual differentiation?
leydig cells (internal/external) and sertoli cells (shuts down female (internal)) sexual differentiation through MID
how does testosterone break down to di hydrotestosterone?
5 alpha reductase
what happens with 5 alpha reductase deficiency
no external male genitalia (penis, scrotum, prostate)
What is the other name for Mayer-Rokitansky-kuster-hauser syndrome?
What is the pneumonic to remember the male internal genitalia?
SEED (seminal vesicles, ejaculatory duct, epididymis, deferens(vas)
Where do the male internal genitalia derive from?
Wolffian (mesonephric) duct
What is the other name for the mesonephric duct?
wolfian duct (male
What are the structures that derive from the mullein (paramesonephric) ducts)
fallopian tubules, uterus, upper part of vagina
What happens in mullein agensis
primary amenorrhea with FULLY developed secondary sex characteristic.
how do sertoli cells work?
shut down female (internal) sexual characteristics (for men) through MIF
what is the karyotype in androgen insensitivity syndrome?
What is imperforate hymen associated with?
simplest defect that results in primary amenorrhea. May be associated with cyclic pelvic pain and a perirectal mass from sequestration of blood in vagina (hemtocolpos)
What is hematocolpos?
perirectal mass from sequestration of blood in vagina
what is the initial Bloodwork in primary amenorrhea?
bhcg, tsh, FSH, LH, prolactin, pelvis US (do they have a uterus?)
High FSH and primary amenorrhea is what ?
What are the major causes of secondary amenorrhea (aside from pregnancy?)
Anorexia, PCOS, stress, excessive exercise, prolactinoma,
when'd o you get bitemporal hemianopsia?
what is the cause of post d &c amenorrhea?
what physical exam findings coincide with secondary amenorrhea?
hyperandrogen, galactorrhea, low weight, high weight
add total testosterone if you are working up what?
What do you do with a high prolactin?
repeat because often false +ve