Blood transfusion reaction Flashcards Preview

Hematology And Oncology > Blood transfusion reaction > Flashcards

Flashcards in Blood transfusion reaction Deck (11):
1

Packed RBCs - dosage effect

increase Hb and O2 carrying capacity

2

Packed RBCs - clinical use

1. acute blood loss
2. severe anemia

3

Platelets transfusion - clinical use

stop significant bleeding (thrombocytopenia, qualitative platelet defects)

4

Platelets transfusion - dosage effect

increases platelet count (5000mm3/unit)

5

Fresh frozen plasma - dosage effect

increase coagulation factor levels

6

Fresh frozen plasma - clinical use

1. DIC
2. Cirrhosis
3. immediate warfarin reversal

7

Cryoprecipitate - dosage effect

contains: 1. fibrinogen 2. fibronectin
3. VWF 4. factor VIII 5. factor XIII

8

Cryoprecipitate - clinical use

coagulation factor deficiencies involving fibrinogen and factor VIII

9

blood transfusion risks

1. infection transmission (low)
2. transfusion reaction
3. iron overload
4. hypocalcemia
5. hyperkalemia

10

blood transfusion risks - hyperkalemia (mechanism)

RBCs may lyse in in old blood units

11

blood transfusion risks - hypocalcemia (mechanism)

citrate is a Ca2+ chelator