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Hematology And Oncology > embryology > Flashcards

Flashcards in embryology Deck (10):
1

fetal erythropoiesis occurs in (and when)

1. yolk sac (3-8 weeks)
2. Liver (6 weeks - birth)
3. Spleen (10-28 weeks)
4. Bone marrow (18 weeks to adult)

2

hemoglobin development - embryogenic globins

ζ and ε

3

hemoglobin development - fetal hemoglobin

HbF (α2γ2)

4

hemoglobin development - adult hemoglobin

HbA1 (α2β2)

5

HBF is the fetal hemoglobin because (relative function)

HbF has higher affinity for 02 due to less avid binding of 2,3-BPG allowing HbF to extract 02 from maternal hemoglobin (HbA1 and HbA2) across the placenta

6

hemoglobin development - α starts approximately at

3 weeks (and platue at 12)

7

hemoglobin development - γ starts approximately at

3 weeks --> platue at 12 --> decrease at 35

8

hemoglobin development - β starts approximately at

3 weeks --> platue at 12 weeks after pregnancy

9

HbA2

α2δ2

10

fetal erythropoiesis occurs in (and when)

1. yolk sac (3-8 weeks)
2. Liver (6 weeks - birth)
3. Spleen (10-28 weeks)
4. Bone marrow (18 weeks to adult)