Calcium Flashcards Preview

Nutritional Biochem > Calcium > Flashcards

Flashcards in Calcium Deck (19)
Loading flashcards...
1

what induces the synthesis of all 3 calcium transport proteins

calcitrol

2

what are the 3 transport proteins of calcium

1. TRPV6
2. calbindin D9K
3. vitamin D dependent calcium ATPase

3

calcium is best sourced in what foods

grains and vegetables

4

what are the 4 enhancers of calcium absorption

1. vitamin D
2. lactose
3. sugar alcohols
4. protein

5

unabsorbed dietary fatty acids form insoluble _____ which are excreted into the feces as

calcium soaps

steatorrhea

6

high plasma phosphorus can ___ calcitriol production in kidneys leading to _____

reduce

reduce calcium absorption

7

when plasma calcium is low, ____ is released from parathyroid gland

PTH (parathyroid hormone)

8

what are the 3 mechanisms PTH return Ca plasma back to normal

1. increase osteoclast activity
2. increases the renal tubular absorption of Ca
3. increases synthesis of calcitriol by activating 1-hydroxylase

9

calcitriol increases production of 3 Ca absorption proteins in ______

enterocytes
1. TRPV6
2. calbindin D9K
3. Ca-ATPase

10

calcitriol increases production of ____ and ___ in the ____

kidney
1. TRPV5
2. calbindin D28K

11

what is released with Ca is too high in the plasma

parafollicular cells of thyroid gland release calcitonin

12

what are the 2 functions of calcitonin

1. inhibit osteoclast activity
2. reduce renal Ca absorption

13

extracellular Ca concentration can be ______ x greater than intracellular

10,000

14

Ca from sarcoplasmic reticulum binds to ____ to initiate the skeletal or cardiac muscle cross bridge cycle

troponin C

15

Ca binds to ______ for smooth muscle contraction

calmodulin

16

each lobe in smooth muscle contraction contains ___ calcium binding sites and thus each calmodulin binds ___ calcium ions

2

4

17

high protein concentration: ___ Ca excretion and ____ Ca absorption

high

high

18

Ca can diminish absorption of ____ and influence serum lipid concentrations

fatty acids (decrease total and LDL cholesterol)

19

increase in Ca intake (600mg or greater): _____ in blood pressure

decrease