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Flashcards in Zinc Deck (18)
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1

____% of intracellular zinc is found inside the nucleus

30-40%

2

best sources of zinc

red meats and seafood

3

what are the 2 major transporters of zinc

1. Zrt
2. Irt-like protein 4 (ZIP4)

4

a mutation in the ZIP4 is known to cause

acrodermatitis enteropathica

5

two families of zinc transporters

1. ZnT family - 10 isoforms
2. ZIP family - 14 isoforms

6

what are the two amino acid transporters of zinc

cysteine and histidine

7

storage of cysteine rich proteins called

metallothionein

8

reduced zinc absorption is _________ with metallothionein formation

directly correlated

9

greater the zinc intake: ____ zinc absorbed

less

10

_____ transports zinc into hepatocytes

ZIP14

11

____ moves zinc out of the body into the intestinal cells and then into the lumen of the GI tract for excretion

ZIP5

12

binds zinc, copper, cadmium, and mercury

metallothionein

13

what are the 7 zinc dependent enzymes

1. carbonic anhydrase
2. alcohol dehydrogenase
3. carboxypeptidase
4. aminopeptidase
5. alkaline phosphate
6. aminolevulinic acid dehydratase (replaces zinc w/ lead)
7. superoxide dismutase (SOD)

14

zinc is a component of the protein _____ (involved in taste acuity)

gustin

15

zinc is needed for structural stability of the storage form of ___ in the granules of _______

insulin
pancreatic B cells

16

zinc deficiency can lead to _____ deficiency

vitamin A

17

______ binds to sites which zinc normally binds (direct inhibitor)

cadmium

18

excess zinc stimulates

thionein synthesis