Malignant (Ewing's and on) Flashcards Preview

Tri 6 - Tumors > Malignant (Ewing's and on) > Flashcards

Flashcards in Malignant (Ewing's and on) Deck (43)
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1

Primitive primary malignant tumor of bone derived from connective tissue framework of bone marrow

Ewing’s Sarcoma

2

Ewing’s Sarcoma age range

10-25 yo peak at 15 years

3

Localized pain with swelling usually palpable soft tissue mass

Ewing’s Sarcoma

4

Only primary malignant bone tumor that
simulates an infection

Ewing’s Sarcoma

5

Fever, Anemia, Leukocytosis, and Elevated ESR

Ewing’s Sarcoma

6

• Permeative
• Wide zone of transition
• Laminated periosteal reaction (or spiculated)
• Codman’s Triangles
• Cortical saucerization is early sign
• Usually mixed lytic and sclerotic patterns

Ewing’s Sarcoma

7

early sign of Ewing's sarcoma

Cortical saucerization

8

Cortical saucerization is due to

subperiosteal extension of tumor through
Haversion systems of cortex

9

MC primary malignant bone tumor to metastasize to bone

Ewing’s Sarcoma

10

Laminated periosteal
reaction seen in

Ewing’s
Sarcoma

11

Produces varying amounts of collagen
in 30-50 yo and presents with Local pain and swelling that may refer pain to joint

Fibrosarcoma

12

1/3 of fibrosarcoma patients present with

pathologic fracture

13

Malignant Fibrous Histiocytoma (MFH)
aka

Undifferentiated Pleomorphic Osteosarcoma
(UPS)

14

Fibrosarcomas are purely _______, with no _______

radiolucent, calcification

15

• Highly destructive lesion
• Expansile
• Medullary in origin
• Permeative, metaphyseal
• Eccentric
• Endosteal scalloping

Fibrosarcoma

16

A secondary Fibrosarcoma
may be caused by

Paget’s disease

17

Fibrosarcoma
usually metastasize to

lung and liver

18

Rare primary malignant bone tumor arising from
vestigial remnants of notochord, which have
persisted in the nucleus pulposus of the IVD

chordoma

19

m/c location for chordoma

Sacrococcygeal chordoma (50%)

20

chordoma can cross the

disc

21

Sacrococcygeal Chordoma will present with

constipation

22

– Increased intracranial pressure, and encroachment
on adjacent structures
– chronic Headache
– Blurred vision, diplopia
– Nasal obstruction
– Cerebellar involvement

Spheno-Occipital Chordoma

23

vertebral cordomas mc affect the __ vertebral body and spares the

C2, posterior elements

24

Presents as localized bone lesion with Dull aching pain, not relieved by rest
but Patient feels fairly good overall

Non-Hodgkin’s Lymphoma
aka Reticulum Cell Sarcoma

25

Non-Hodgkin’s Lymphoma Tumor begins in

medullary bone

26

Laminated periosteal reaction and Pathological fracture is common (initial complaint)

Non-Hodgkin’s Lymphoma

27

radiograph of 51-year-old man with left leg pain demonstrates a
lytic lesion with a moth-eaten appearance centered in the mid
diaphysis of the tibia

Non-Hodgkin’s Lymphoma

28

usually more symptomatic than blastic lesions

Lytic lesions

29

Primary site of skeletal involvement for Hodgkin’s Lymphoma of Bone

vertebral body

30

Hodgkin’s Lymphoma of Bone is also common in

lower thoracic and upper lumbar spine