Flashcards in Microbiology Part 1 Deck (33)
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1
Phagocytic cells of the immune system
neutrophils, monocytes, macrophages
2
present antigen to T cells,
starts as Monocyte
macrophages
3
can inactivate pathogens
natural killer cells
4
3 main types of T cells
killer T, helper T and Regulatory T
5
triggers target to commit "suicide"
killer T cells
6
help in antigen recognition and regulation
helper T cells
7
keeps other T cells under control
regulatory T cells
8
target of antibody and T cells
antigen
9
where antibody binds on antigens
epitope
10
present antigen for T cells to see
Histocompatibility Complex Proteins
11
found on surface of most cells,
iinforms Killer T cells of whats goin on INSIDE cell
Class 1 HCP
12
made by antigen presenting cells (macrophages), informs helper T cells of problems OUTSIDE cells
class 2 HCP
13
plants the "kiss of death"
antibody (opsonization)
14
very fast system of 20 different proteins made by the liver consisting of 3 different pathways
Complement system
15
3 different pathways of the Complement System
classical (depends of antibodies)
Alternative (antibody independnt)
Lectin activation path
16
mannose binds lectin leading to the attraction of phagocytes
lectin activation pathway (complement system)
17
T cell mediated hypersensitivity
Type IV
18
caused by proteins from mold or plant spores
hay fever
19
caused by dust mites, cockroaches, rodents, and household pets
asthma
20
allergic reponse cells that degranulate
mast cells
21
self-reactive T cells,
myelin sheaths destroyed,
CNS
multiple sclerosis
22
Activated T cells can cross the BBB
multple sclerosis
23
90% women,
inflammation of lungs, arthritis, kidney damage, hair loss, paralysis and convulsions, caused by breakdown of B and T cells that make IgG antibodies
Lupus
24
Thymic tissue missing,
Bubble boy,
No T cells
DiGeorge syndrome
25
no T or B cells
Severe Combined Immunodeficiency Syndrome
26
Pneumocystis carinii
AIDS
27
Sabin
live and attenuated virus
28
Salk
Kills virus
29
Generates memory helper T and B cells but not memory killer T cells
Noninfectious vaccines (salk)
30
