Newman - Lymphoma and Leukemia, LAD Flashcards Preview

Hematology and Oncology > Newman - Lymphoma and Leukemia, LAD > Flashcards

Flashcards in Newman - Lymphoma and Leukemia, LAD Deck (18):
1

Large cell with multiple or multi-lobulated nuclei. CD15+, CD30+

Reed-Sternberg cell

2

List the three B symptoms - systemic symptoms important in staging.

1. Unexplained fever 39C (~103F) degrees
2. Wt loss >10% total body over last three months
3. Drenching night sweats

3

When should someone undergo CHEST RADIOGRAPHY BEFORE undergoing lymph nodebiopsy?

Any patient with persistent, unexplained LAD unassociated with obvious underlying inflammatory or infectious process.
Use to identify the presence or absence of a large mediastinal mass.

4

***Burkitt Location of tumor in..
1. Sporadic
2. Endemic/Africa

1. Abdomen
2. Head and neck

5

***What accounts for 97% of childhood malignancies?

Acute leukemias (subtypes: AML, ALL; but ALL much more common in children)

6

Trisomy 21 increases risk for what neoplasm?

ALL and AML

7

AML is more likely in what age range in a child with Down Syndrome?

Less than 3 years old

8

Marker for hematologic malignancies

LDH

9

When do you biopsy?

If an enlarged supraclavicular node is palpated ALONG WITH other findings (B symptoms, multiple nodes, abnormal CXR or CT) that are consistent with malignancy.

10

NHL epidemiology - part of what notable genetic syndrome?

Ataxia-telangiectasia

11

A unilateral, large painful node with unremitting fever (104-105F) for 5 days.

Kawasaki

12

Girl does not feel well. Tender swelling in L axilla and fever. Began shaving a few weeks ago. Most likely etiology?

Infectious

possibly incise and drain.

13

Tularemia

rabbits

14

Cat Scratch organism

bartonella henselae

15

Yersinsia

plague

16

6yo with fever and swollen L axillary adenopathy. Tender, non fluctant. Healing skin lesion on hand. Questionable liver tenderness, border at 2cm below RCM at MCL.

What is this and treat with what?

Cat scratch

Treat with azithromycin

17

Supraclavicular lymph node, scrotal swelling NT/firm, fatigue, cough, nose bleeds - what is this and what two things indicate CXR?

This is Lymphoblastic Lymphoma.
1. Testicular mass esp painless w/o hx of trauma or injury ->likely malignant
2. Generalized LAD wiht respiratory symptoms.

18

Neuroretinitis is an uncommon manifestation of what disease?
Macular star - exudates overlying macular, radiating outward.

Cat scratch disease