Robbins Chapter 13 - WBC Diseases and Spleen/Thymus Flashcards Preview

Hematology and Oncology > Robbins Chapter 13 - WBC Diseases and Spleen/Thymus > Flashcards

Flashcards in Robbins Chapter 13 - WBC Diseases and Spleen/Thymus Deck (6):
1

Platelets, RBC, and Leukocytes - origin, transport, and residency

Platelets and RBC - originate in marrow, live in blood
Leukocytes (monocytes, granulocytes, lymphocytes) - originate in marrow, live in TISSUE

2

name for a juvenile granulocyte. Major feature is an indented nucleus

metamyelocyte

3

Lymphocyte markers:
T-helper, T-cytotoxic, B-Cell, NK-cell

T-helper - CD4
T-cytotoxic - CD4
B-Cell - CD19
NK-cell - CD56/16

4

If alkylating agents or anti-cancer agents are used, think what broad type of WBC disorder?

Leukopenia - agranulocytosis

5

Ulcerating lesions of gingiva, floor of mouth, buccal mucosa, pharynx, or elsewhere in oral cavity are characteristic of what?

Infection as the consequence of agranulocytosis that causes leukopenia.

6

What compensatory change occurs in marrow due to leukopenia?

hypercellularity