Flashcards in Chlamydia Deck (6):
What is chlamydia?
- Chlamydia is the most prevalent sexually transmitted infection in the UK and is caused by Chlamydia trachomatis, an obligate intracellular pathogen.
- Approximately 1 in 10 young women in the UK have Chlamydia. The incubation period is around 7-21 days, although it should be remembered a large percentage of cases are asymptomatic.
What are the features of chlamydia?
- asymptomatic in around 70% of women and 50% of men
- women: cervicitis (discharge, bleeding), dysuria
- men: urethral discharge, dysuria
What are the potential complications?
- pelvic inflammatory disease
- increased incidence of ectopic pregnancies
- reactive arthritis
- perihepatitis (Fitz-Hugh-Curtis syndrome)
What investigations would you carry out?
- traditional cell culture is no longer widely used
- nuclear acid amplification tests (NAATs) are now rapidly emerging as the investigation of choice
- urine (first void urine sample), vulvovaginal swab or cervical swab may be tested using the NAAT technique
What is the approach to screening?
- In England the National Chlamydia Screening Programme is open to all men and women aged 15-24 years
- The 2009 SIGN guidelines support this approach, suggesting screening all sexually active patients aged 15-24 years
- Relies heavily on opportunistic testing