Flashcards in Syphilis - Treponema pallidum Deck (7):
What is syphilis?
- Syphilis is a sexually transmitted infection caused by the spirochaete Treponema pallidum.
- Infection is characterised by primary, secondary and tertiary stages.
- The incubation period is between 9-90 days
What are the primary features of syphilis?
- chancre - painless ulcer at the site of sexual contact
- local non-tender lymphadenopathy
- often not seen in women (the lesion may be on the cervix)
What are the secondary features of syphilis?
- systemic symptoms: fevers, lymphadenopathy
- rash on trunk, palms and soles
- buccal 'snail track' ulcers (30%)
- condylomata lata
What are the tertiary features of syphilis?
- gummas (granulomatous lesions of the skin and bones)
- ascending aortic aneurysms
- general paralysis of the insane
- tabes dorsalis
- Argyll-Robertson pupil
What are the features of congenital syphilis?
- blunted upper incisor teeth (Hutchinson's teeth), 'mulberry' molars
- rhagades (linear scars at the angle of the mouth)
- saber shins
- saddle nose
How do you treat syphilis?
1) I.M. Benzylpenecillin (doxycycline and tetracycline alternatives if allergy)
3) late infections large doses of I.V. penecillin for 10 days, if allergic ceftriaxone