Final Exam Review Flashcards

1
Q

Which are the zinc-dependent toxins?

A

Botulinum and tetanus

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2
Q

One of the first signs of schistosomiasis infection is _________.

A

pruritus

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3
Q

What are immunotoxins?

A

Toxins that are guided to certain cells (such as tumors) with antibodies

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4
Q

During the latent period, virus ____________.

A

is being replicated in the cell, but no virus particles are being assembled

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5
Q

Which toxin requires calcium and calmodulin to become active?

A

Antrax edema factor

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6
Q

What does terbinafine kill and how?

A

Fungus, by the accumulation of intracellular toxins

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7
Q

Nystatin is a ______ anti-fungal.

A

topical

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8
Q

Bacteria that require vitamins, amino acids, and growth factors are called _______.

A

fastidious

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9
Q

The _______ are the organs that are most affected by schistosomiasis infection.

A

liver and bladder

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10
Q

Bordadella pertussis works by ________.

A

inhibiting phagocytosis

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11
Q

tetM is transferred on ________.

A

conjugative transposons

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12
Q

Cholera toxin works by ______________.

A

raising intracellular cAMP

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13
Q

MacKonkey agars select for __________.

A

Gram-negative bacteria

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14
Q

Two lactose fermentators that could be found on a MacKonkey agar are __________.

A

E. coli and Klebsiella

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15
Q

C. diphtheria toxin results from __________.

A

lysogenic conversion

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16
Q

Staph food poisoning results from _______.

A

ingestion of preformed toxin

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17
Q

Glycocalyx is made by ________.

A

Staphylococcus epidermis

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18
Q

C. perfringens can also be found in _________.

A

healthy people

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19
Q

Gram-negative rod with intrinsic resistance to penicillin, ceftriaxone, and erythromycin?

A

P. aeruginosa

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20
Q

Lacking cell wall?

A

Mycoplasma

21
Q

Antigenically distinct pili?

A

Neisseria

22
Q

Antigenically distinct capsule?

A

Streptococcus pneumoniae

23
Q

Both _____________ cannot be cultured.

A

chlamydia and mycoplasma

24
Q

Spastic paralysis is _________, while flaccid paralysis is ________.

A

tetanus; botulinum

25
Q

Describe bacteria on Hektoen agars.

A

Salmonella (green with black dots); Shigella (green with green dots); everything else (salmon)

26
Q

The most likely bacteria to acquire erm is ______.

A

Staph

27
Q

_______ can acquire gyrase mutations that induce resistance to fluoroquinolones.

A

Both Gram-negative and Gram-positive

28
Q

First-generation cephalosporins have spectra of action similar to ________.

A

amoxicillin

29
Q

______ can acquire mutations in PBPs.

A

Staph, Neis, and Strep

30
Q

Of cephalosporins, aminoglycosides, fluoroquinolones, and erythromycin, which is least effective against P. aeruginosa?

A

Erythromycin

31
Q

Aminoglycosides can kill ________.

A

Gram-negative aerobic bacilli

32
Q

Which organisms can tetracyclines kill that macrolides cannot?

A

Gram-negative rods

33
Q

In addition to MSSA, ______ also contains a beta-lactamase.

A

Klebsiella

34
Q

Can amoxicillin kill Pseudomonas?

A

No! Only piperacillin can

35
Q

B. fragilis can be killed by _________.

A

metronidazole, ertapenem, amoxicillin-clavulanate, tetracyclines, pip-taz, and clinamycin

36
Q

What three drugs/drug categories kill Neisseria?

A

Ceftriaxone, macrolides, and tetracyclines

37
Q

What three categories of drugs kill atypical bacteria?

A

Macrolides, tetracyclines, and fluoroquinolones

38
Q

Which antibiotics inhibit the hepatic metabolism of co-administered drugs?

A

Erythromycin and metronidazole

39
Q

Which fluoroquinolone is hepatically metabolized?

A

Ciprofloxacin

40
Q

Which antibiotic causes oral thrush?

A

Doxycycline (metronidazole can exacerbate existing infections)

41
Q

Aminoglycosides only treat ________.

A

Gram-negative aerobic bacilli

42
Q

Bactrim kills _________.

A

Gram-positive, Gram-negative, and atypical bacteria

43
Q

Which can kill Pseudomonas, tetracyclines or fluoroquinolones?

A

Fluoroquinolones

44
Q

Which bacterial class is photosensitizing?

A

Doxycycline

45
Q

Can clindamycin kill Gram-negative rods

A

Only Bacteroides, but primarily just Gram-positives and anaerobes

46
Q

Can vancomycin kill Bacteroides?

A

Nope!

47
Q

Compared to clarithromycin, azithromycin has the advantages of ___________.

A

being longer lasting, killing mycoplasma in a single dose, and does not inhibit liver enzymes

48
Q

Which class of antibiotics can prolong QT?

A

Macrolides