Skin Manifestations of Systemic Disorders Flashcards Preview

Dermatology > Skin Manifestations of Systemic Disorders > Flashcards

Flashcards in Skin Manifestations of Systemic Disorders Deck (109)
Loading flashcards...
1

Characteristics of Pyoderma Gangrenosum

Rapidly evolving
Idiopathic
Chronic & severely debilitating ulcerative skin disease

2

Associated Underlying Inflammatory or Malignant Disease Presenting with Pyoderma Gangrenosum

Chronic UC
Crohn's disease
Chronic active hepatitis
Hematologic malignancies
Rheumatoid arthritis

3

Hx of Pyoderma Gangrenosum

Acute onset
Painful hemorrhagic pustule
Painful nodule surrounding by erythematous halo

4

PE Findings of Pyoderma Gangrenosum

Breakdown with ulcer formation with dusky red or purple borders
Irregular & raised
Boggy with perforations that drain pus

5

Most Common Sites for Pyoderma Gangrenosum

Lower extremities
Buttocks
Abdomen

6

Treatment of Pyoderma Gangrenosum

Treat underlying disease
Avoid trauma
High dose systemic corticosteroids
Systemic immunosuppression

7

Types of Systemic Immunosuppression

Sulfasalazine
Cyclosporine
Infiximab

8

Diabetic Associations with Skin Issues

Acanthosis nigricans
Necrobosis lipoidica diabeticorum (NLD)
Granuloma annulare
Thrush
Intertrigo

9

Characteristics of Acanthuses Nigricans

Velvety thickening & hyper pigmentation of the skin

10

Acanthosis Nigricans is Associated with what Issues

Diabetes
Insulin resistant syndromes
Obesity
Internal malignancy (GI most common)

11

History with Acanthuses Nigricans

Insidious onset
Darkening of pigmentation

12

PE Findings of Acanthosis Nigricans

Hyperpigmentation
Velvety looking
Skin line accentuated
Surface become wrinkled or creased

13

Most Common Sites for Acanthosis Nigricans

Axilla
Neck (back & sides)
Groin
AC fossae

14

Treatment of Acanthosis Nigricans

R/O DM
Treat associated disorder
Usually none required

15

PE Findings of Necrobiosis Lipoidica Diabeticorum (NLD)

Oval, violaceous patch
Advancing border is red
Central area turns yellow-brown
Telangiectasias
Ulceration possible esp. after trauma
Usually anterior surface of the legs

16

Treatment of Necrobiosis Lipoidica Diabeticorum (NLD)

Difficult
Refer to derm
DM control doesn't determine presence of NLD

17

Type 1 DM Trifecta

PVD
Neuropathy
Sugar everywhere

18

Characteristics of Granuloma Annular

Self limiting
Asymptomatic
Chronic dermatosis
Slight association with DM

19

History of Granuloma Annular

Slowly increases over months
Duration variable

20

PE Findings of Granuloma Annular

Smooth, shiny firm ring of flesh colored papule & plaques
Annular with central depression

21

Most Common Sites of Granuloma Annular

Dorm of hands & feet
Extremities
Trunk

22

Treatment of Granuloma Annular

Not necessary
If needed: potent topical steroids, or intralesional injections of steroids

23

Characteristics of Intertrigo

Irritation in the skin folds
Worse with heat & moisture

24

Intertrigo Associated With

DM
HIV
Obesity

25

Intertrigo Related to

Candida
Fungus irritation
Secondary bacterial infection

26

Most Common Sites of Intertrigo

Axilla
Groins
Gluteal folds
Overlapping abdominal panniculus

27

PE Findings of Intertrigo

Erythema
+/- pruritis
Tenderness
Erythematous plaques

28

Treatment of Intertrigo

Keep cool & dry
Treatment based on cause

29

What should be avoided in the treatment of intertrigo?

Steroids: fungus will spread rapidly

30

Describe Thrush

White plaques or red erosive areas in the oral mucosa