Topical Medications Flashcards Preview

Dermatology > Topical Medications > Flashcards

Flashcards in Topical Medications Deck (115)
Loading flashcards...
1

Dependent Factors of Success of Dermatologic Therapies

Correct diagnosis
Type of lesion treated
Medication used
Vehicle (cream, ointment, etc.)
Method used to apply medication

2

What does the vehicle determine?

Rate at which the active ingredient is absorbed through the skin

3

Components of the Vehicle

Solvents
Stabilizers
Emollients
Humectants
Thickening agents
Emulsifying agents

4

What is acute inflammation treated with?

Aqueous drying preparations

5

What is chronic inflammation treated with?

Greasy, lubricating compounds

6

Important Factors of Drug Penetration

Method of topical application
Site of application
Thickness of epidermal layer

7

Define Tachyphylaxis

Progressive decrease in clinical response due to repetitive application of drug
Similar to tolerance

8

Solution for Tachyphylaxi

Drug free intervals
Switch at various times to alternative agents (down a strain, different base)

9

3 Basic Ingredients of Vehicles

Powder
Oils
Liquids

10

Types of Vehicles

Powders
Solutions
Tinctures
Lotions
Oils
Ointments
Creams
Gels
Aerosols & Sprays
Shampoos
Foam

11

What vehicles should we be most concerned about?

Ointments
Lotions
Creams
Gels

12

What do powders aid in?

Absorbing moisture
Decrease friction
Help cover wide areas easily

13

Where is the best place to use powders?

Intertriginous areas

14

Define Solutions

Lotions with very minimal oil or solid content, but with active ingredients
Ex: Visine

15

Define Tinctures

Alcoholic or hydroalcohoic solutions

16

Define Lotions

Suspension of powder in water

17

Define Shake Lotions

Solids are suspended within
Ex: Calamine lotion

18

Define Emollient Lotions

Oils dispersed in the water usually with surfactant

19

Where are lotions useful?

Hairy areas
Conditions where large areas have to be treated

20

Least Potent Topical Therapy

Lotions

21

Define Creams

Semisolid emulsions of oil in water about equal proportion
Penetrates stratum corneum well

22

Define Ointment

Water droplets suspended in the continuous phase of oil or of inert bases
Ex oil: mineral oil
Ex inert bases: petrolatum (vaseline)

23

Use of Ointments

Most lubricating & moisturizing
Facilitates heat retention
Semi-occlusive
Non-seborrheic, non-intertriginous areas

24

Most Potent Vehicle

Ointment

25

Define Gels

Transparent semisolid emulsion that liquefies on contact with skin
Dries as thin, greaseless, non-occlusive film

26

Uses for Gels

Seborrheic areas (face, chest)
Considered drying
Exudative inflammation (poison ivy)
Acne (Retin-A)

27

Aerosols & Sprays

Alcohol based solutions
Pressurized
Considered drying
Wasteful
Scalp most frequently

28

Define Foams

Pressurized collections of gaseous bubbles in a matrix of liquid film

29

Shampoo uses

Seborrheic dermatitis of the scalp

30

Main Educational Point of Shampoos

Left on for 5-7 minutes