SM_218a: Cartilage Histology Flashcards Preview

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Flashcards in SM_218a: Cartilage Histology Deck (23)
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1

Cartilage is ______

Cartilage is rubbery, flexible matrix that covers the ends of bones

2

What are the functions of cartilage?

Functions of cartilage

  • Supports body
  • Helps articulate joints
  • Provides attachment sites for muscles
  • Gives structure to certain parts of the body
  • Improves flexibility
  • Acts as scaffold for bone development

3

Cartilage includes a _____ component and a _____

Cartilage includes a cellular component (chondrocytes) and matrix component

4

Three types of cartilage are _____, _____, and _____

Three types of cartilage are hyaline cartilage, elastic cartilage, and fibrocartilage

5

Hyaline cartilage is a ______

Hyaline cartilage is a homogeneous matrix of predominantly type II collagen and proteoglycans with chondrocytes

 

(most prevalent)

6

Elastic cartilage has ____ fibers within the ____

Elastic cartilage has elastic fibers within the matrix

7

Fibrocartilage has _____ running through the _____

Fibrocartilage has type I collagen fibers running through the matrix

8

______ helps fibrocartilage resist ______ forces

Collagen helps fibrocartilage resist compressive forces

9

______ pattern is pathognomonic for fibrocartilage

Herring bone pattern is pathognomonic for fibrocartilage

 

(also called chevron pattern)

10

Hyaline cartilage is found in ______

Hyaline cartilage is found in long bones

11

Elastic cartilage is found in the ______ and ______

Elastic cartilage is found in the ear and epiglottis

12

Fibroelastic cartilage is found in the ______ and ______

Fibroelastic cartilage is found in the intervertebral discs and pubic symphysis 

 

(resists compressive forces)

13

_____ covers the cartilage

Perichondrium covers the cartilage

14

_____ is required for something to be cartilage

Lacunar space is required for something to be cartilage

15

Darker matrix (immature) is _____ matrix, while lighter matrix (mature) is _____

Darker matrix (immature) is territorial matrix, while lighter matrix (mature) is interterritorial

16

____ are proliferating cartilage

Isogenous groups are proliferating cartilage

17

Matrix of cartilage is composed of _____, _____, and _____ 

Matrix of cartilage is composed of type II collagen, proteoglycans and glycosaminoglycans, and structural glycoproteins

 

 

 

18

Matrix of cartilage is predominantly ______ collagen

Matrix of cartilage is predominantly type II collagen

 

 

(also types VI, IX, X, XI to interconnet component fibers and cells)

19

_____ and _____ form complexes with negative charges and bind with water to give the matrix its viscosity, strength, and flexibility

Proteoglycans and glycosaminoglycans form complexes with negative charges and bind with water to give the matrix its viscosity, strength, and flexibility

 

(hyaluronic acid is the largest GAG)

20

_____ is the largest glycosaminoglycan

Hyaluronic acid is the largest glycosaminoglycan

21

_____ attach cells to the matrix in cartilage

Structural glycoproteins attach cells to the matrix in cartilage

22

Describe the development of cartilage

Development of cartilage

  1. Everything is cartilage at the beginning
  2. Cartilage develops into bone through endochondrial ossification or intramembranous ossification and the remaining cartilage becomes mature cartilage

23

Zones during ossification include _____, _____, _____, and _____

Zones during ossification include zone of ossification, zone of hypertrophy, zone of proliferation, and reserve cartilage

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