1 - Repro - Origin of the Sexes Flashcards Preview

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Flashcards in 1 - Repro - Origin of the Sexes Deck (30):
1

From which layer of the bilaminar disc does do the primordial germ cells develop from?

Epiblast

2

What determines whether the primordial gonads develop into ovaries or testes?

Whether they are colonised by a germ cell with XX or XY chromosomes

3

What part of the primordial gonad does a germ cell with XX chromosomes colonise?

Cortex

4

What part of the primordial gonad does a germ cell with XY chromosomes colonise?

Medulla

5

Name the gene expressed by Sertoli cells, which drives male development:

SRY gene

6

Which cell expresses the SRY gene which drives Male development?

Sertoli cells

7

What is the average length of the vas deferens?

~ 30-45 cm

8

Which part of the male genitalia develops from the urogenital sinus?

Prostate
Bulbourethral glands
Urethra

9

Which part of the male genitalia develops from the mesonephric duct?

Epidydimis
Vas deferens
Seminal vesicles

10

Which part of the female genitalia develops from the urogenital sinus?

Vagina

11

Which part of the female genitalia develops from the paramesonephric ducts?

Fallopian tubes
Uterus
Cervix

12

List some secondary female sex characteristics:

- Hair growth
- Breast development
- Subcutaneous fat redistribution (around hips, buttocks and thighs)
- Elbows hyperextend 5-8' more than males

13

List some male secondary sex characteristics:

- Hair growth
- Change in body composition: more muscle:fat
- Enlargement of larynx = voice deepens
- Larger hands, feet and nose
- Broadening of shoulders and chest

14

What is another name for the Wolffian ducts?

Mesonephric ducts

15

What is another name for the Mullerian ducts?

Paramesonephric ducts

16

Name the ducts from which the male genitalia develop from:

Mesonephric/Wolffian ducts

17

Name the ducts from which the female genitalia develop from:

Paramesonephric/Mullerian ducts

18

What ensures the regression of the Mullerian ducts for male development?

Mullerian Inhibitory Hormone (MIH) release from Sertoli cells

19

What substance is secreted by Sertoli cells causing the regression of the Mullerian ducts?

Mullerian Inhibitory Hormone (MIH)

20

What substance supports the development of the Mesonephric/Wolffian ducts?

Androgens

21

Name the parts of the external genitalia of an indifferent embryo:

- Genital tubercle
- Genital swelling
- Genital fold
- Urethral fold

22

What parts of the female external genitalia form from the urethral folds and genital swelling?

Labia minora
Labia majora

23

What part of the female external genitalia form from the genital tubercle?

Clitoris

24

Which hormone is vital for the closing of the urethral folds, for the development of the penis?

Dihydrotestosterone

25

Which part of the male external genitalia form from the genital swelling?

Testes

26

Which part of the male external genitalia form from the genital tubercle?

Glans penis

27

Name the remnant of the gubernaculum:

Males = Scrotal ligament
Females = Round ligament of the uterus + Ovarian ligament

28

Describe the location from where the testes and ovaries arise:

Upper lumbar area of posterior abdominal wall

29

In approx. which month of development do the testes reach the iliac fossa?

~ 3rd month

30

In approx. which month of development do the testes enter the inguinal canal?

~ 7th month