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Flashcards in Antibiotics Deck (41):
1

Which antibiotics should be avoided in a penicillin allergy?

Penicillins
Cephalosporins (eg ceftraixone)
Carbapenems (meropenem)

2

Which is the antibiotic of choice for a mild community acquired pneumonia in a penicillin allergic patient?

Oral as mild
Avoid penicillins and cephalosporins
Erythromycin/clarithromycin (macrolide)
Clarithro better as less nausea and only BD

3

Which 3 antibiotics should be used for exacerbations of chronic bronchitis?

Amoxicillin, clarithromycin or tetracycline

4

Which abx is recommended in CAP?

Amoxicillin (fluclox to eradicate staph if superimposed on flu)
Eythromycin/clari if pen allergic

5

Which abx is recommended in atypical pneumonia?

Clarithromycin (macrolide)

6

Which abx are recommended in HAP?

<5 days of admission: co-amoxiclav or cefuroxime
>5 days after admission: piperacillin with tazobactam OR a broad-spectrum cephalosporin (e.g. ceftazidime) OR a quinolone (e.g. ciprofloxacin)

7

Name 2 abx recommended for lower UTI

Nitrofurantoin or
Trimethoprim

8

Name 2 abx recommended for pyelonephritis

Broad spectrum cephalosporin (caftazidime) or
Quinolone (ciprofloxacin)

9

Treatment of acute prostatitis

Quinolone (cipro) or
Trimethoprim

10

Recommended treatment of impetigo

Fusidic acid (topical)
If widespread, oral flucloxicillin/erythromycin

11

Recommended treatment of cellulitis

Flucloxicillin
Clarithromycin if pen allergic

12

Recommended treatment of animal/human bites

Co-amoxiclav
doxycyline+metronidazole if pen allergic

13

Recommended treatment of mastitis

Flucloxicillin

14

Recommended treatment of throat infections

Penicillin V (phenoxymethylpenicillin)
erythromycin if pen allergic

15

Recommended treatment of sinusitis/otitis media

Amoxicillin (erythro)

16

Recommended treatment of otitis externa

Flucloxicillin (erythro)

17

Peridontal abscess treatment

Amoxicillin
Ulcerating/necrotising Metronidazole

18

Recommended treatment of gonorrhoea

IM ceftriaxone + oral azithromycin (macrolide)

19

Recommended treatment of chlamydia

Doxycycline (tetracycline) or azithromycin (macrolide)

20

Recommended treatment of PID

Ofloxacin (quinolone) + metronidazole OR
IM ceftriaxone (cephalosporin) + metronidazole + doxycycline (tetracycline)

21

Recommended treatment of syphilis

Benzathine penicillin or doxycycline (tetracycline) or erythromycin (macrolide)

22

Recommended treatment of BV

Oral/topical metronidazole or topical clindamycin

23

Treatment of 1st episode of C diff

Metronidazole

24

Treatment of recurring C diff

Vancomycin (glycopeptide)

25

Treatment of campylobacter enteritis

Clarithromycin (macrolide)

26

Treatment of salmonella

Ciprofloxacin (quinolone)

27

Treatment of Shigellosis

Ciprofloxacin (quinolone)

28

Which antibiotics are most likely to cause C diff?

Broad spectrum
Cephalosporins most likely
Penicillins
Clindamycin
Quinolones (ciprofloxacin)

29

Treatment of C diff

1st line oral metronidazole for 10-14days
2nd line/if severe oral vancomycin
Life threatening IV metro + vanc

30

Main SE of metronidazole (and class)

Nitromidazole
Peripheral neuropathy
Interacts with alcohol

31

Which abx should be avoided in pts taking statins? Why?

Clarithromycin
P450 enzyme inhibition, increases risk of rhabdomyolysis

32

What abx is used prophylactically in sickle cell disease?

Phenoixymethylpenicillin
erythromycin if pen allergic

33

How is blepharitis treated if simple hygiene methods fail?

Chloramphenicol 1% eye drops

34

When should quinolones be prescribed with caution?

Epilepsy
Children (arthropathy)

35

1st line treatment of meningitis in 20yr old

Cefotaxime
Aciclovir
Dexamethasone

36

Which abx is linked with steven-johnson syndrome?

Sulfamethoxazole (co-trimoxazole)
All sulfonamides

37

Which abx is linked with peripheral neuropathy?

Metronidazole

38

What is the early treatment of Lyme's disease?

Doxycycline

39

Management of neutropenic sepsis

Immediately start piperacillin with tazobactam (Tazocin)

40

Management for an MRSA carrier?

Nasal mupirocin
Chlorhexidine for the skin

41

Which antibiotic reacts with alcohol?

Metronidazole