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Flashcards in Pregnancy Deck (24):
1

Which antibiotics are contraindicated in pregnancy?

Tetracyclines (tetracycline, doxycycline)
Aminoglycosides (gentamycin, streptomycin, neomycin)
Sulfonamides (sulfadiazine, sulfamethoxazole)
Trimethroprim
Quinolones (ciprofloxacin, norfloxacin)

2

Which antihypertensives are contraindicated in pregnancy?

ACEi
AngIIRB

3

Which antihypertensives are recommended in pregnancy?

Labetalol (1st line)
Methyldopa
Amlodipine/nifedipine

4

Which anti-epileptics are thought to be safer in pregnancy?

Aarbamazepine
Lamotrigene

5

Which antiepileptic is the worst in pregnancy?

Sodium valproate

6

Which diabetic drugs are contraindicated in pregnancy?

Sulfonylureas (gilclazide, gilbenclamide, glimepiride)

7

If a pregnant lady has a clotting disorder, what do they do?

Avoid warfarin
switch to LMWH

8

Effect of ACEi in pregnancy?

Teratogenic
Renal dysgensis
Craniofacial abnormalities

9

Effect of aminoglycosides in pregnancy?

teratogen: ototoxicity

10

Effects of antiepileptics in pregnancy?

Teratogen
Neural tube defects

11

Effect of chloramphenicol in pregnancy

grey baby syndrome

12

Effect of cocaine in pregnancy

IUGR, premature labour

13

Effect of poorly controlled DM?

Macrosomia
Neural tube defects
Polyhydramnios
Prem labour
Shoulder dystocia

14

Effect of tetracyclines in pregnancy

Discoloured teeth

15

Effect of thalidomide in pregnancy

Limb reduction defects

16

Effect of warfarin in pregnancy?

Craniofacial abnormalities

17

Which antibiotics should be avoided while breastfeeding?

Ciprofloxacin
Chloramphenicol
Tetracycline
Sulphonamides (sulfamethoxazole)

18

Which psych drugs should be avoided while breastfeeding?

Lithium, benzodiazepines, clozapine

19

Which heart drugs should be avoided while breastfeeding?

Amiodarone
Aspirin (Reye's)

20

Which laxative is 1st line in pregnancy?

Ispaghula husk

21

When should contraceptive patches be avoided? (not combined hormonal contraception in general)

In those with BMI>35
Reduced efficacy if weigh >90kg

22

What is the issue with drugs in the 1st trimester?

Teratogenesis
Congenital malformations (esp 3-11weeks)

23

What is the issue with drugs in the 2nd and 3rd trimester?

Growth and functional development of fetus
Toxic effect on fetal tissues

24

Which drugs affect breastfeeding itself?

Phenobarbital reduces infant sucking reflex
Bromocriptine affects lactation