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Flashcards in Cardiac Deck (13):
1

Name 5 classes of drugs that can elongate the QT interval

Antipsychotics
Antidepressants
Antibiotics
Antiarrhythmics
Antihistamines

2

Name 10 drugs that can elongate the QT interval

Antipsychotics (haloperidol, risperidone)
Antidepressants (citalopram, amitryptiline)
Antibiotics (clarithromycin, erythromycin- macrolides)
Antiarrhythmics (sotalol, amiodarone)
Antihistamines (loratadine, cetirizine)

3

What drugs can cause hyperkalaemia?

Potassium sparing diuretics, ACE inhibitors, angiotensin 2 receptor blockers, spironolactone, ciclosporin, heparin

4

Name 5 drugs that may exacerbate heart failure

Pioglitazone (fluid retention)
verapamil (-ve inotrope)
NSAIDs (fluid retention) apart from low dose aspirin
Steroids (fluid retention)
Flecainide (-ve inotrope)

5

Name 5 drugs that cause QT prolongation

Methadone
Escitalopram
Domperidone
Ondansetron
Ciprofloxacin

6

What is particular about isosorbide mononitrate prescribing?

Give second dose after 8hrs
Gives 4hrs for levels to fall to reduce tolerance
(unless modified release)

7

Cutaneous SE of amiodarone

Slate grey skin

8

Which drug must be avoided with beta blockers?

Verapamil
Increased risk of heart block

9

Main SE ivabradine

Visual effects (bright spots)
Headache
Bradycardia

10

Swollen lips and tongue caused by what class of cardiac drug?

Angiodema
ACEi

11

Main SE of amlodipine

CCB
Ankle swelling
Headache, flushing

12

What is needed other than drug levels to diagnose digoxin toxicity?

K+ levels (hypokalaemia can precipitate toxicity)
ECG

13

Management of digoxin toxicity

Digibind
Correct arryhthmias
Monitor K+