Flashcards in Epilepsy Deck (30)
What is ictus?
any acute event, refers to the epilepsy attack itself
Aetiology of epilepsy?
mass lesion in skull
what are the main neurotransmitters involved in epilepsy?
GABA (inhibitory) and glutamate (excitatory)
in simple partial seizure, does patient remain conscious or lose consciousness?
what are deja vu and jamais vu examples of
complex partial seizures
treatment of absence seizures?
pals --> sodium valproate and ethosuxamide
side effects of sodium valproate?
gerry little side effects
10% will have hair loss
reduces efficacy of COCP
May go pale
may be noticed by teacher in school?
what happens during tonic phase of a seixzure?
how long does tonic phase last?
what happens during clonic phase
• Eye rolling
• No breathing
status epileptics is a seizure lasting ?
over 30 minutes
when would you do a CT scan?
if you think its a stroke
head injury with seizure
driving - how long can you not drive for after seizure ?
if you have a seizure, how long can you not drive a HGV?
how long seizure free before driving a car?
12 months, or 3 years during sleep
how long do you have to be seizure free for and off medication to drive a HGV?
what is encephalitis?
inflammation of the brain parenchyma
most common cause of encephalitis?
herpes simplex virus
does sodium valproate cause weight gain or weight loss?
what can they do to the efficacy of the pill?
precipitants of status epilepticus?
Severe metabolic disorders
hyponatraemia, pyridoxine deficiency
Abrupt withdrawl of anti-convulsants Treating absence seizures with CBZ
management of status epilepticus?
Emergency blood tests +/- CT
Anti convulsants ( Phenytoin (check levels)
side effects of ethosuxamide?
diziness, nausea, anorexia
1st line for focal/partial seizures?
side effects of carbamazepine?
diziness, GI disturbance, water retention, SKIN RASH
main side effect of digoxin?
which drug causes gum hypertrophy?
phenytoin, which is also teratogenic and causes arrhythmias
method of action of lamotrigine?
inhibits sodium channels