Epilepsy Flashcards Preview

Neurology > Epilepsy > Flashcards

Flashcards in Epilepsy Deck (30)
1

What is ictus?

any acute event, refers to the epilepsy attack itself

2

Aetiology of epilepsy?

trauma
hypoxia
pyrexia
mass lesion in skull
drugs
CNS infections
vascular abnormalities

3

what are the main neurotransmitters involved in epilepsy?

GABA (inhibitory) and glutamate (excitatory)

4

in simple partial seizure, does patient remain conscious or lose consciousness?

remains

5

what are deja vu and jamais vu examples of

complex partial seizures

6

treatment of absence seizures?

pals --> sodium valproate and ethosuxamide

7

side effects of sodium valproate?

gerry little side effects
10% will have hair loss
reduces efficacy of COCP

8

Childhood onset
Patient stares
May go pale
may be noticed by teacher in school?

absence seizure

9

what happens during tonic phase of a seixzure?

Rigid
Epileptic cry
Tongue biting
Incontinence
Hypoxia

10

how long does tonic phase last?

10-60 seconds

11

what happens during clonic phase

• Convulsions
• Eye rolling
• Tachycardia
• No breathing

12

status epileptics is a seizure lasting ?

over 30 minutes

13

when would you do a CT scan?

if you think its a stroke
focal signs
head injury with seizure

14

driving - how long can you not drive for after seizure ?

6 months

15

if you have a seizure, how long can you not drive a HGV?

5 years

16

how long seizure free before driving a car?

12 months, or 3 years during sleep

17

how long do you have to be seizure free for and off medication to drive a HGV?

10 years

18

what is encephalitis?

inflammation of the brain parenchyma

19

most common cause of encephalitis?

herpes simplex virus

20

does sodium valproate cause weight gain or weight loss?

weight gain

21

what can they do to the efficacy of the pill?

reduce

22

precipitants of status epilepticus?

Severe metabolic disorders
hyponatraemia, pyridoxine deficiency
Infection
Head trauma
Sub-arachnoid haemorrhage
Abrupt withdrawl of anti-convulsants Treating absence seizures with CBZ

23

management of status epilepticus?

ABC
Emergency blood tests +/- CT
Anti convulsants ( Phenytoin (check levels)
Keppra
valproate
Benzodiazepines)

24

side effects of ethosuxamide?

diziness, nausea, anorexia

25

1st line for focal/partial seizures?

carbamazepine

26

side effects of carbamazepine?

diziness, GI disturbance, water retention, SKIN RASH

27

main side effect of digoxin?

blurred vision

28

which drug causes gum hypertrophy?

phenytoin, which is also teratogenic and causes arrhythmias

29

method of action of lamotrigine?

inhibits sodium channels

30

side effects of lamotrigine?

han (nausea, diziness, ataxia)