Flashcards in myasthenia graves and LES Deck (10)
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1
MG - autoantibodies to ?
post synaptic Ach receptors
2
features of MG?
muscles become progressively weaker after periods of activity and slowly improve after rest
3
what conditions is MG associated with?
autoimmune conditions such as SLE
4
Where on the body does MG affect?
face, neck, limb girdles, eyes, dysphagia and diplopia
5
why do you get diplopia?
extra ocular muscle weakness
6
Investigations MG?
single fibre electromyography
CT to exclude thyoma
7
CK levels in MG?
normal
8
treatment of MG?
long acting acetylcholine esterase
pyridostigmine MGP
9
what do you get antibodies against in Lambert Eaton Syndrome?
pre synaptic voltage gated calcium channels
10