myasthenia graves and LES Flashcards Preview

Neurology > myasthenia graves and LES > Flashcards

Flashcards in myasthenia graves and LES Deck (10)
Loading flashcards...
1
Q

MG - autoantibodies to ?

A

post synaptic Ach receptors

2
Q

features of MG?

A

muscles become progressively weaker after periods of activity and slowly improve after rest

3
Q

what conditions is MG associated with?

A

autoimmune conditions such as SLE

4
Q

Where on the body does MG affect?

A

face, neck, limb girdles, eyes, dysphagia and diplopia

5
Q

why do you get diplopia?

A

extra ocular muscle weakness

6
Q

Investigations MG?

A

single fibre electromyography

CT to exclude thyoma

7
Q

CK levels in MG?

A

normal

8
Q

treatment of MG?

A

long acting acetylcholine esterase

pyridostigmine MGP

9
Q

what do you get antibodies against in Lambert Eaton Syndrome?

A

pre synaptic voltage gated calcium channels

10
Q

what is lambert eaton syndrome associated with/

A

small cell lung cancer