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Flashcards in General Neurology Deck (19)
1

If the lesion is above the anterior horn cell (i.e. spinal cord, brain stem, motor cortex). what kind of sign would this give?

upper motor neurone sign

2

LOWER MOTOR NEURONE SIGN. where is the lesion?

the lesion is either in the anterior horn cell or distal to the anterior horn cell (i.e. anterior horn cell, root, plexus, peripheral nerve)

3

increased reflexes - upper motor neurone sign or lower?

upper

4

arreflexia - upper or lower?

lower

5

increased muscle tone (spasticity), upper or lower?

upper

6

weakness and wasting (atrophy) in the muscle(s), upper or lower?

lower

7

muscle wasting ?

this is a lower motor neurone sign

8

generally flexors weaker than extensors in the legs and the reverse in the arms. what kind of weakness is this known as?

pyramidal pattern of weakness

9

hyper reflexia, upper or lower ?

upper (respond quickly)

10

exaggerated law jerk, upper or lower?

upper

11

fasciculations, u or l?

lower (shaking)

12

what is picks disease a form of ?

frontotemporal dementia

13

picks disease characterised by?

personality change and impaired social conduct

14

inserting inappropriate objects in mouth, disinhibition, increased appetite and perseveration behaviours?

picks disease

15

what macroscopic changes would you get in picks disease?

Pick bodies - spherical aggregations of tau protein (silver-staining)
Gliosis
Neurofibrillary tangles
Senile plaques

16

you get Atrophy of the frontal and temporal lobe. What is characteristic of picks

Focal gyral atrophy with a knife-blade appearance

17

gold standard test for cervical myelopathy ?

An MRI of the cervical spine

18

treatment for restless leg syndrome ?

ropinorole (Restless leg Ropinorole)

19

Symmetrical muscle weakness, that usually begins in the lower legs, and ascends to the upper limbs, and even the face. Occurs several weeks after viral illness?

guillan barre syndrome