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Flashcards in Neurophysiology Deck (30):
1

What is an action potential

brief electrical impulse resulting in membrane potential being momentarily reversed

2

where is the site of initiation of the all or none action potential in a neuron

axon hillock

3

describe a unipolar neuron

1 neurite
peripheral autonomic neuron

4

describe a pseudounipolar neuron

1 neurite that bifurcates
dorsal root ganglion

5

describe a bipolar neuron

2 neurites
retinal neuron

6

describe a multipolar neuron

>=3 neurites
motor neurons
LMN

7

What is the overall ion movement in upstroke in an action potential

Na influx

8

What is the overall ion movement in downstroke in action potential

K efflux

9

what is membrane resistance

holes/channels that allow for ion leakage

10

What is length constant

distance a passive process travels

11

high membrane resistance means there are no leakages, true or false

true

12

higher the membrane resistance, the higher/lower the axoplasm resistance, the higher/lower the length constant

higher the membrane resistance, lower the axoplasm resistance, higher the length constant

13

increasing axon diameter increases/decreases axoplasm resistance

decreases

14

adding an insulating material increases/decreases membrane resistance

increases

15

myelinated axons conduct faster than non-myelinated axons, true or false

true

16

2 ways of increasing passive current spread

decrease axoplasm resistance with thicker axons
increase membrane resistance with myelin

17

What types of synapses exist

axodendritic - commonest
axosomatic
axoaxonic - least common

18

What is the major excitatory neurotransmitter

glutamine

19

in the excitatory synapses, what are the properties of the receptor

cation, selective, ionotropic, glutamate receptors

20

what are the major inhibitory neurotransmitters

GABA
glycine

21

in the inhibitory synapse, what are the properties of the receptor

anion, selective, ionotropic, GABA/glycine receptors

22

Of which ion is there an influx in epsp

Na+ influx

23

Of which ion is there an influx in ipsp

Cl- influx

24

What types of gating are present in neurotransmitter receptors

direct gating
indirect gating

25

What receptor is involved in direct gating

ionotropic receptors

26

What are ionotropic receptors and how fast is transmission

receptors that are also channels
rapid transmission

27

What receptor is involved in indirect gating

metabotropic receptors

28

What are metabotropic receptors and how fast is transmission

receptor with NO channel
slow transmission

29

NMDA receptors are permeable to which ions

Ca, Na, K

30

Non-NMDA receptors are permeable to which ions

Na, K