Block 5 highish yield Flashcards Preview

IHO week 6 and Final > Block 5 highish yield > Flashcards

Flashcards in Block 5 highish yield Deck (35)
1

reduced IL-2 and expression of IL-2R (CD25) is a result of:

reduced antigen exposure

2

no Tregs

IPEX

3

problem caused by IPEX

out of control T-cells

4

Treg autocrine cytokine?

IL-35

5

genetic cause of IPEX

mutated FOXP3

6

overexpression of thyroid hormones

Grave's disease

7

high MHC II induces

Th1

Th17

8

low MHC II induces

Th2

9

CXCR3

CCR5

Th1

10

CCR3

CCR4

CCR8

Th2

11

CCR6

Th17

12

Mutation in CCR5

HIV resistance

13

anti-nuclear antibodies

SLE

14

dsDNA and Smith (Sm) antigen antibodies

SLE

15

SLE hypersensitivity

Type III

immune complex mediated

16

anti-phospholipid antibodies

SLE

17

acute necrotizing vasculitits

SLE

18

SS-A

HLA-DR3

Subacute cutaneous LE

19

autoantibodies for CCPs

RA

20

dry eyes

dry mouth

SS-A

SS-B

Sjogren Syndrome

21

perivascular fibrosis

systemic sclerosis

22

Scl-70 antibodies

systemic sclerosis

23

anti-centromere antibodies

CREST syndrome

24

Raynaud's

systemic sclerosis

25

anti-U1-RNP

mixed connective tissue disease

26

Btk

XLA

27

B-cells present

don't differentiate into plasma cells

CVID

28

failure of thymus development

DiGeorge

29

22q11

DiGeorge

30

X-linked recessive CD40L mutation

Hyper IgM syndrome

31

P. jiroveci

Hyper IgM syndrome

32

defect in humoral and cell mediated immunity

usually X-linked gamma chain cytokine receptor mutation

SCID

33

ADA

SCID

34

Thrombocytopenia

Eczema

variable loss of cell mediated immunity

Wiskott-Aldrich

35

inability to clear EBV

infectious mono

B cell lyphoma

X-linked lymphoproliferative disorder