Flashcards in Neoplasia Deck (46)
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1
slow growing, encapsulated mass of orderly cells, no invasion
benign tumor
2
fast growing, invasive mass of disorderly cells, not encapsulated
malignant tumor
3
tumor is large and localized
primary malignancy
4
tumor is small and multifocal
metastatic malignancy
5
genetic mutation linked with some cancers
oncogene
6
gene which governs the growth of normal tissue
proto-oncogene
7
chemicals, radiation, or germs that may cause cancer
carcinogens
8
agents capable of causing genetic material; may cause cancer
mutagens
9
change in one base; neurofibromatosis, adenomatous polyposis coli
DNA point mutation
10
gene segments are exchanged; Burkitt's lymphoma, leukemia
translocation
11
gene segment is duplicated; N-myc is neuroblastoma
amplification
12
gene which prevents normal cells from becoming malignant
cancer suppressor gene
13
inactivation of cancer suppressor genes; BRCA in breast cancer
anti-oncogenes
14
Starry-sky appearance on histo; HHV type 4 ARBO virus
Burkitt's lymphoma
15
Binucleated cells; associated with Hodgkin's lymphoma
Reed Sternberg cells
16
ARBO virus linked with Burkitt's lymphoma
Epstein-Barr virus
17
Linked with hepatocellular carcinoma
Hepatitis C
18
Malignant plasma cells, Bence Jones protein, recurrent infections
multiple myeloma
19
benign smooth muscle tumor in the uterus
uterine leiomyoma
20
Blood malignancy with numerous immature WBC's
leukemia
21
leukemia m/c in young children
acute lymphocytic leukemia
22
leukemia associated with Auer rods in adults
acute myelogenous leukemia
23
leukemia associated with the Philadelphia chromosome
chronic myelogenous leukemia
24
translocation involving chromosome 9 and 22
Philadelphia chromosome
25
leukemia m/c in 60+ patients; asymptomatic
chronic lymphocytic leukemia
26
linked with nitrosamine and alcohol use; squamous cell type
esophageal cancer
27
linked with exposure to asbestos; malignancy of the pleura
mesothelioma
28
linked with exposure to benzene
Leukemia
29
linked with exposure to aflatoxin for moldy groundnuts or corn
hepatocellular carcinoma
30
