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Flashcards in Week 11 - Lactation Deck (10)
1

Describe the structure of the breasts

-Mammary glands embedded within lobulated masses of tissue separated by fibrous/adipose tissue
-Lobes contain alveoli, lactiferous ductules and blood vessels

2

What is mammogenesis? Describe what happens

-The preparation of the breasts for lactation during pregnancy
-Hypertrophy of the duct-lobe-alveolar system

3

When is milk production possible in pregnancy?

-From trimester 2

4

Why does pregnancy favour growth of breasts over secretion of milk?

-High progesterone:oestrogen

5

What is lactogenesis? Describe this stage

-Synthesis of milk
-Fats and proteins and sugars are secreted and synthesised by sER and golgi.
-Neutrophils/macrophages enter alveolar space to protect against infection

6

What is galactokinesis? Describe this

-Ejection of milk
-Let-down reflex -> alveoli are surrounded by myoepithelia and contract in response to oxytocin

7

What stimulates oxytocin release in order to stimulate the let-down reflex?

-Mechanical stimulation of breast and nipple eg suckling

8

What is galactopoesis? Explain how this works

-Maintenance of lactation
-Prolactin is stimulated by suckling and causes the production of milk for the next feed which is stored in the alveoli and ducts (secretory change)

9

State some situations when lactation would cease

-Stopped suckling -> lost feedback of prolactin
-Pain
-Menstruation
-Prolactin supression
-Age due to breast involution

10

Descrbe the changes in milk which occur from a few days to mature milk

-Begins as colostrum which has a high protein and igG count
-Turns into mature milk with an increase in water and fats and proteins such as lactalbumin