Flashcards in Week 8.1 - Maternal problems in Pregnancy Deck (37)
Describe the anatomical changes to the GI tract during pregnancy
-Alterations in the disposition of the viscera eg appendix moves to RUQ as uterus enlarges
Describe the physiological changes which occur in the GI tract during pregnancy
-Smooth muscle relaxation by progesterone -> delayed emptying -> constipation
-Biliary tract stasis
-Increased risk of pancreatitis
Describe the haematological changes which occur during pregnancy
-Prothrombotic state with increased fibrin deposition at implatation site and increased fibrinogen and clotting factors in blood.
-Reduced fibrinolysis and changes in vascular flow due to venodilation
Why cant you give warfarin in thromboembolic disease of pregnancy?
-Warfarin can cross the placenta and is teratogenic
What causes anaemia during pregnancy?
-Plasma volume increases more than red cell mass -> physiological anaemia
-Can also be due to Fe or folate deficiencies
Describe changes in the immune system during pregnancy
-Non-specific suppression of the local immune responses at the materno-fetal interface