Week 8.1 - Maternal problems in Pregnancy Flashcards Preview

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Flashcards in Week 8.1 - Maternal problems in Pregnancy Deck (37)
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31

Describe the anatomical changes to the GI tract during pregnancy

-Alterations in the disposition of the viscera eg appendix moves to RUQ as uterus enlarges

32

Describe the physiological changes which occur in the GI tract during pregnancy

-Smooth muscle relaxation by progesterone -> delayed emptying -> constipation
-Biliary tract stasis
-Increased risk of pancreatitis

33

Describe the haematological changes which occur during pregnancy

-Prothrombotic state with increased fibrin deposition at implatation site and increased fibrinogen and clotting factors in blood.
-Reduced fibrinolysis and changes in vascular flow due to venodilation
-Anaemia

34

Why cant you give warfarin in thromboembolic disease of pregnancy?

-Warfarin can cross the placenta and is teratogenic

35

What causes anaemia during pregnancy?

-Plasma volume increases more than red cell mass -> physiological anaemia
-Can also be due to Fe or folate deficiencies

36

Describe changes in the immune system during pregnancy

-Non-specific suppression of the local immune responses at the materno-fetal interface

37

Give 2 diseases which can occur due to transfer of antibodies across the placenta

-Haemolytic disease of the newborn
-Graves disease